INHBE
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Official Full Name
inhibin, beta E -
Overview
INHBE is a member of the activin beta family (see INHBA; MIM 147290) that plays a role in pancreatic exocrine cell;growth and proliferation (Hashimoto et al., 2006 (PubMed 16426570)). -
Synonyms
INHBE;inhibin, beta E;inhibin beta E chain;activin;MGC4638;Activin beta E chain;INHB E;Inhibin beta E;activin beta E;OTTHUMP00000242578;activin beta-E chain
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- HEK293
- Mammalian Cells
- Wheat Germ
- In Vitro Cell Free System
- His
- GST
- Non
- Avi
- Fc
Involved Pathway
INHBE involved in several pathways and played different roles in them. We selected most pathways INHBE participated on our site, such as Cytokine-cytokine receptor interaction,TGF-beta signaling pathway,Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with INHBE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | IFNGR2,TNFRSF25,MET,CCR8L,TNFRSF21,Pdgfa&Pdgfb,Il23a,IL-15RA,IL17RB,KITLGA |
| Signaling pathways regulating pluripotency of stem cells | PIK3CB,WNT2B,MAPK11,MAPK3,PIK3CA,PIK3R5,AXIN2,IL6ST,PIK3CG,PCGF5 |
| TGF-beta signaling pathway | ID4,ACVR2B,RBL1,SMAD7,SMAD3,ACVR2AA,CUL1B,TGFBR2,TGFB1,TGFBR1A |
Protein Function
INHBE has several biochemical functions, for example, cytokine activity,growth factor activity,hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INHBE itself. We selected most functions INHBE had, and list some proteins which have the same functions with INHBE. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | STC2A,GCGB,GNRH2,FNDC5B,LEPB,C19orf80,TTR,ADCYAP1A,METRNL,NPPB |
| growth factor activity | RABEP1,NGF,COL20A1,IGF2A,GDNFA,VEGFAA,GFER,NTF7,BMP8B,MDK |
| cytokine activity | Il1f6,IL17F,IL16,IFNG1-2,PRL7D1,IL10,TNFSF4,CSF2,Kitl,TNFSF18 |
| transforming growth factor beta receptor binding | SMAD2,LRG1,BMP5,GDF1,FKBP1A,SMAD3,LFT1,INHBA,GDF6B,LFT2 |
Interacting Protein
INHBE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INHBE here. Most of them are supplied by our site. Hope this information will be useful for your research of INHBE.
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References
- Ng, CF; Xu, JY; et al. Identification of FHL2-Regulated Genes in Liver by Microarray and Bioinformatics Analysis. JOURNAL OF CELLULAR BIOCHEMISTRY 115:744-753(2014).
- Ansari, D; Andersson, R; et al. Protein deep sequencing applied to biobank samples from patients with pancreatic cancer. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 141:369-380(2015).
