INFG
-
Official Full Name
Interferon-Gamma -
Overview
Interferon-gamma (IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-γ, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-γ expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-γ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFN-γ is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. -
Synonyms
IFNG;IFG;IFI;Immune interferon, type II interferon;T cell interferon;MAF;IFN-gamma;Interferon gamma;Interferon gamma precursor;interferon, gamma
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|
Involved Pathway
INFG involved in several pathways and played different roles in them. We selected most pathways INFG participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with INFG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
INFG has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by INFG itself. We selected most functions INFG had, and list some proteins which have the same functions with INFG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
INFG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INFG here. Most of them are supplied by our site. Hope this information will be useful for your research of INFG.
Resources
Related Services
Related Products
References
