IMPAD1
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Official Full Name
inositol monophosphatase domain containing 1 -
Synonyms
IMPAD1;inositol monophosphatase domain containing 1;inositol monophosphatase 3;FLJ20421;IMPA3;IMP 3;IMPase 3;Inositol monophosphatase domain containing protein 1;Myo inositol monophosphatase A3;OTTHUMP00000226649;golgi-resident PAP phosphatase;myo-inositol monophosphatase A3;inositol-1(or 4)-monophosphatase 3;inositol monophosphatase domain-containing protein 1;Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase;GPAPP
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- Human
- Sus scrofa (Pig)
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Xenopus laevis
- Callithrix jacchus (White-tufted-ear marmoset)
- zebrafish
- CHO
- Mammalian Cells
- Insect Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
IMPAD1 involved in several pathways and played different roles in them. We selected most pathways IMPAD1 participated on our site, such as Inositol phosphate metabolism,Sulfur metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with IMPAD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Inositol phosphate metabolism | TPI1A,PLCE1,MTMR7B,INPP4B,INPP1,CDIPT,NUDT4,PLCD3A,ITPK1,PIP5K1C |
Phosphatidylinositol signaling system | TMEM55A,PIK3CB,CALML5,PIK3C3,ITPKB,ITPR3,PRKCB,INPP5K,PTENA,DGKZ |
Metabolic pathways | GBE1,POLR2L,ST3GAL3B,URAH,glpK,PGM2,TM7SF2,ALDH1B1,ADO,NOS1 |
Sulfur metabolism | SUOX,CYCS,MPST,PAPSS1,PAPSS2B,CYCSB,SQRDL,BPNT1,PAPSS2A,TST |
Protein Function
IMPAD1 has several biochemical functions, for example, 3(2),5-bisphosphate nucleotidase activity,3-nucleotidase activity,inositol monophosphate 1-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IMPAD1 itself. We selected most functions IMPAD1 had, and list some proteins which have the same functions with IMPAD1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
inositol monophosphate 3-phosphatase activity | IMPA2,IMPA1 |
magnesium ion binding | WEE2,NUDT16,NLK,GCLC,PIF1,HMGCL,SERPINB1A,THTPA,ARF1,ENO1A |
inositol monophosphate 4-phosphatase activity | IMPA1,IMPA2 |
inositol monophosphate 1-phosphatase activity | IMPA2,IMPA1 |
3(2),5-bisphosphate nucleotidase activity | BPNT1 |
Interacting Protein
IMPAD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IMPAD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IMPAD1.
Resources
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References
- Nizon, M; Alanay, Y; et al. IMPAD1 Mutations in Two Catel-Manzke Like Patients. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 158A:2183-2187(2012).
- Styer, JC; Keddie, J; et al. Genomic organization and regulation of the LeIMP-1 and LeIMP-2 genes encoding myo-inositol monophosphatase in tomato. GENE 326:35-41(2004).
- Pari, K; Mueller, GA; et al. Solution structure of the RNase H domain of the HIV-1 reverse transcriptase in the presence of magnesium. BIOCHEMISTRY 42:639-650(2003).
- Kuznetsova, E; Xu, LD; et al. Structure and Activity of the Metal-independent Fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae. JOURNAL OF BIOLOGICAL CHEMISTRY 285:21049-21059(2010).