IMP4
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Official Full Name
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) -
Overview
IMP4 forms a ternary complex with IMP3 (MIM 612980) and MPP10 (MPHOSPHO10; MIM 605503) that interacts with U3 small;nucleolar RNA (snoRNA), which is required for the early cleavage steps in pre-rRNA processing (Granneman et al., 2003;(PubMed 12655004)). -
Synonyms
IMP4;IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast);U3 small nucleolar ribonucleoprotein protein IMP4;BXDC4;MGC19606;D1Wsu40e;U3 snoRNP protein 4 homolog;U3 snoRNP protein IMP4;Brix domain containing protein 4;Brix domain-containing protein 4;IMP4_HUMAN;LRRGT00017
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Chicken
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
IMP4 involved in several pathways and played different roles in them. We selected most pathways IMP4 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with IMP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | NOB1,EMG1,RBM28,cka2,DKC1,WDR75,DROSHA,UTP15,NXF2,TBL3 |
Protein Function
IMP4 has several biochemical functions, for example, protein binding,rRNA primary transcript binding,snoRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IMP4 itself. We selected most functions IMP4 had, and list some proteins which have the same functions with IMP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| rRNA primary transcript binding | PTRF,NCL,RPF1 |
| protein binding | RBBP7,MAMSTR,TUB,HOXB6,PEX2,PDCD4,MOCS3,CDC25B,BEX2,HIST1H3A |
| snoRNA binding | IMP3,PWP2,NOP56,DDX21,NUDT1,NUDT16L1,UTP15,NHP2,PWP2H,UTP6 |
Interacting Protein
IMP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IMP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of IMP4.
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References
- Granneman, S; Gallagher, JEG; et al. The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes. NUCLEIC ACIDS RESEARCH 31:1877-1887(2003).
