IKZF4
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Official Full Name
IKAROS family zinc finger 4 (Eos) -
Overview
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development. -
Synonyms
IKZF4;IKAROS family zinc finger 4 (Eos);zinc finger protein, subfamily 1A, 4 (Eos) , ZNFN1A4;zinc finger protein Eos;Eos;Eos protein;IKAROS family zinc finger 4;Ikaros family zinc finger protein 4;IKZF4_HUMAN;KIAA1782;Zinc finger protein Eos (IKAROS family zinc finger protein 4);ZNFN1A4;OTTHUMP00000243022;OTTHUMP00000243025;OTTHUMP00000243026;zinc finger transcription factor Eos;zinc finger protein, subfamily 1A, 4 (Eos)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IKZF4-8107M | Recombinant Mouse IKZF4 Protein | Mammalian Cells | Mouse | His |
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| IKZF4-851HCL | Recombinant Human IKZF4 cell lysate | Human | Non |
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| IKZF4-4489M | Recombinant Mouse IKZF4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| IKZF4-4489M-B | Recombinant Mouse IKZF4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
IKZF4 involved in several pathways and played different roles in them. We selected most pathways IKZF4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IKZF4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
IKZF4 has several biochemical functions, for example, bHLH transcription factor binding,metal ion binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IKZF4 itself. We selected most functions IKZF4 had, and list some proteins which have the same functions with IKZF4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ITGAX,ZNF285A,PDE8A,ZNHIT6,ZFPM2A,CSH2,COL5A2,ZFP161,NADK,RSAD1 |
| bHLH transcription factor binding | TCF4,RUNX2,ISL1,SOX9,TCF3A,ASCL1,MAP3K10,LMO2,SMAD3,PSMD9 |
| transcription regulatory region DNA binding | HIVEP2,FOXC1,PAX2,HIVEP3,FOXA1,BRCA1,TBX21,ZNF649,ZFP746,MSX2 |
| sequence-specific DNA binding | ZNF274,ARX,TBX1,NFIL3-2,FOXF2,VDRB,SALL3,GSX1,HESX1,RX2 |
| protein heterodimerization activity | ADRB1,UNC13A,AXL,ATF4,SOX8,BCL2L1,GCA,HIST1H3H,BMP6,PRMT5 |
| protein homodimerization activity | BOKB,HES1,KIAA1804,PSPH,SLC22A6,MAOB,NR2F2,CARM1,ZFP423,DNTTIP1 |
| transcription factor activity, sequence-specific DNA binding | DBPA,TCEAL1,ZFP1,IRF9,POU6F1,WT1B,SUPT6H,RBPJL,MTA2,CEBPD |
Interacting Protein
IKZF4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IKZF4 here. Most of them are supplied by our site. Hope this information will be useful for your research of IKZF4.
NFKBIA;FHL2
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