IGSF1
-
Official Full Name
immunoglobulin superfamily, member 1 -
Overview
This gene encodes a member of the immunoglobulin-like domain-containing superfamily. Proteins in this superfamily contain varying numbers of immunoglobulin-like domains and are thought to participate in the regulation of interactions between cells. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
IGSF1;immunoglobulin superfamily, member 1;immunoglobulin superfamily member 1;IGCD1;IGDC1;INHBP;KIAA0364;MGC75490;PGSF2;Immunoglobulin like domain containing protein 1;Inhibin binding protein;p120;Pituitary gland specific factor 2;inhibin-binding protein;pituitary gland-specific factor 2;immunoglobulin-like domain-containing protein 1
Recombinant Proteins
- Rat
- Human
- Chicken
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- Avi
- Fc
Involved Pathway
IGSF1 involved in several pathways and played different roles in them. We selected most pathways IGSF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IGSF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
IGSF1 has several biochemical functions, for example, coreceptor activity,inhibin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGSF1 itself. We selected most functions IGSF1 had, and list some proteins which have the same functions with IGSF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GDF5,GLS2,CCNA2,NRBF2,TSR2,KIAA1609,HIST3H3,SMURF1,OFD1,SDHA |
| coreceptor activity | RGMB,CXCR7,RGMD,ACKR3B,CXCR6,RGMA,TGFBR3,ACVR2A,TMIGD2,NRP1 |
| receptor activity | NOTCH1,NLGN3B,IL18R1,CADM1,KLRK1,IGF2R,KLRB1F,ANPEP,ADIPOR1,CHRM3 |
| inhibin binding | INHA,INHBA,ACVR1B,ACVR2A |
Interacting Protein
IGSF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGSF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGSF1.
RANBP10;HECTD1
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References
- Samanta, D; Almo, SC; et al. Nectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity. CELLULAR AND MOLECULAR LIFE SCIENCES 72:645-658(2015).
- Nitschke, L; et al. CD22 and Siglec-G regulate inhibition of B-cell signaling by sialic acid ligand binding and control B-cell tolerance. GLYCOBIOLOGY 24:807-817(2014).
