IGLL1
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Official Full Name
immunoglobulin lambda-like polypeptide 1 -
Overview
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
IGLL1;immunoglobulin lambda-like polypeptide 1;lambda 5;ig lambda-5;immunoglobulin lambda chain 5;CD179 antigen-like family member B;Igll;Igl-5;Lambda5;BB139905
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His&T7
- His
- Non
- Avi&Fc&His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IGLL1-107H | Recombinant Human IGLL1 protein, T7/His-tagged | E.coli | Human | His&T7 | 38-213 a.a. |
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| IGLL1-5410C | Recombinant Chicken IGLL1 | Mammalian Cells | Chicken | His |
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| Igll1-5647M | Recombinant Mouse Igll1 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Val112~Ala206 |
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| IGLL1-7554H | Recombinant Human IGLL1, His-tagged | E.coli | Human | His | 38-213aa |
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| IGLL1-8082M | Recombinant Mouse IGLL1 Protein | Mammalian Cells | Mouse | His |
|
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| IGLL1-5258HCL | Recombinant Human IGLL1 293 Cell Lysate | HEK293 | Human | Non |
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| IGLL1-1205H | Recombinant Human IGLL1 Protein (Leu29-Ser201), N-His tagged | E.coli | Human | His | Leu29-Ser201 |
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| IGLL1-4264H | Recombinant Human IGLL1 Protein (Met1-Ser213), C-His tagged | Mammalian Cells | Human | His | Met1-Ser213 |
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| IGLL1-4475M | Recombinant Mouse IGLL1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| IGLL1-4475M-B | Recombinant Mouse IGLL1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
IGLL1 involved in several pathways and played different roles in them. We selected most pathways IGLL1 participated on our site, such as Primary i,nodeficiency, which may be useful for your reference. Also, other proteins which involved in the same pathway with IGLL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| nodeficiency | UNG,TAP2, Cd79b,RAG2,AIRE,RAG1,ICOS,RFXANK,RFXAP,TNFRSF13B |
| Primary i | AIRE,CD3D,CD19,CD8B1,ZAP70,IL2RG,CD79A,UNG,TAP1,LCK |
Protein Function
IGLL1 has several biochemical functions, for example, antigen binding,immunoglobulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGLL1 itself. We selected most functions IGLL1 had, and list some proteins which have the same functions with IGLL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| immunoglobulin receptor binding | CLEC4D,FES,IGLC2,Ighg,IGKC,Ighg2b,FGR,Ighg2a,IgG3 |
| antigen binding | SPON2,IGLC2,Ighg2b,CD40,HNRNPM,IL7R,Ighg2a,MHC1UKA,LILRA1,TOPORS |
Interacting Protein
IGLL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGLL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGLL1.
ltp_ebvg;q9wmx2-pro_0000037551;IGHG1;MME;CD9
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References
- Luo, T; Kuriakose, JA; et al. Ehrlichia chaffeensis TRP120 Interacts with a Diverse Array of Eukaryotic Proteins Involved in Transcription, Signaling, and Cytoskeleton Organization. INFECTION AND IMMUNITY 79:4382-4391(2011).
- Wang, Y; Kanegane, H; et al. Novel Ig alpha (CD79a) gene mutation in a Turkish patient with B cell-deficient agammaglobulinemia. AMERICAN JOURNAL OF MEDICAL GENETICS 108:333-336(2002).
