IGHG3
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Official Full Name
Immunoglobulin heavy constant gamma 3(G3m marker) -
Overview
Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants. -
Synonyms
IGHG3;Immunoglobulin heavy constant gamma 3(G3m marker)
Recombinant Proteins
- Human
- Mouse
- HEK293
- Human Cells
- Mouse Serum
- Human Plasma
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IGHG3-176H | Recombinant Human IGHG3 protein | HEK293 | Human | Glu99-Lys377 |
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| IGHG3-20H | Recombinant Human IGHG3 protein | HEK293 | Human | Non | Glu 99 - Lys 377 |
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| IGHG3-7373H | Recombinant Human IGHG3, None tagged | Human Cells | Human | Non |
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| IgG3-1606MCL | Recombinant Mouse IgG3 cell lysate | Human Cells | Mouse | Non |
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| IGHG3-120H | Native Human Immunoglobulin G3 | Mouse Serum | Human | Non | Full length native human IgG3 |
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| IGHG3-231H | Native Human Immunoglobulin G3 (IgG3) | Human Plasma | Human | Non |
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| Ighg3-7302M | Recombinant Mouse Ighg3 protein | HEK293 | Mouse | Glu97-Lys329 |
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| IGHG3-928H | Recombinant Human IGHG3 Protein (SPR verified) | HEK293 | Human | Glu99-Lys377 |
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Involved Pathway
IGHG3 involved in several pathways and played different roles in them. We selected most pathways IGHG3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IGHG3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
IGHG3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by IGHG3 itself. We selected most functions IGHG3 had, and list some proteins which have the same functions with IGHG3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
IGHG3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGHG3 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGHG3.
Resources
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References
- Eguchi-Ogawa, T; Toki, D; et al. Structure of the genomic sequence comprising the immunoglobulin heavy constant (IGHC) genes from Sus scrofa. MOLECULAR IMMUNOLOGY 52:97-107(2012).
- Dechavanne, C; Guillonneau, F; et al. Mass Spectrometry Detection of G3m and IGHG3 Alleles and Follow-Up of Differential Mother and Neonate IgG3. PLOS ONE 7:-(2012).
