IGHG2
-
Official Full Name
Immunoglobulin heavy constant gamma 2 (G2m marker) -
Overview
Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants. -
Synonyms
DKFZp686I04196;G2m marker;Ig gamma 2 chain C region;IGHG 2;IGHG2;Immunoglobulin heavy constant gamma 2;Immunoglobulin G 2;IgG2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IGHG2-548H | Recombinant Human IGHG2 protein | HEK293 | Human | Glu99-Lys326 |
|
Involved Pathway
IGHG2 involved in several pathways and played different roles in them. We selected most pathways IGHG2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IGHG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
IGHG2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by IGHG2 itself. We selected most functions IGHG2 had, and list some proteins which have the same functions with IGHG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
IGHG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGHG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGHG2.
Resources
Related Services
Related Products
References
- Jackson, KJL; Wang, Y; et al. Human immunoglobulin classes and subclasses show variability in VDJ gene mutation levels. IMMUNOLOGY AND CELL BIOLOGY 92:729-733(2014).
- Butler, JE; Wertz, N; et al. Porcine IgG: structure, genetics, and evolution. IMMUNOGENETICS 61:209-230(2009).
