IGBP1
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Official Full Name
IGBP1 immunoglobulin (CD79A) binding protein 1 -
Overview
CD79 is a dimeric transmembrane protein that is associated with membrane immunoglobulin and initiates B-cell signaling following engagement of the latter by antigen.1-3 The 2 component chains of CD79, referred to as CD79a and CD79b. CD79a as well as CD79b is purported to be a B cellspecific antigen. CD79a expression begins at the earliest pro-B stage of development and continues throughout Bcell differentiation to the plasma cell stage,6 making it one of the most useful panB-cell markers used in routine immunophenotypic analysis. In addition, CD79a expression seems to be restricted to B-lineage cells (ie,a diagnostically specific B-cell marker). -
Synonyms
IGBP1;immunoglobulin (CD79A) binding protein 1;IBP1;immunoglobulin-binding protein 1;alpha 4;protein alpha-4;CD79a-binding protein 1;renal carcinoma antigen NY-REN-16;B cell signal transduction molecule alpha 4;B-cell signal transduction molecule alpha 4;protein phosphatase 2A, regulatory subunit alpha-4;bA351K23.1 (immunoglobulin binding protein 1 (CD79A) );ALPHA-4
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Human Cells
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
IGBP1 involved in several pathways and played different roles in them. We selected most pathways IGBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IGBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
IGBP1 has several biochemical functions, for example, mitogen-activated protein kinase kinase binding,protein binding,protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGBP1 itself. We selected most functions IGBP1 had, and list some proteins which have the same functions with IGBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex binding | NFYB,TWF1,TUB,PTK2B,LZTFL1,CDK5RAP1,RPTOR,KRT8,TG,UQCRC2 |
| protein binding | PTPRE,SEMA4D,RASGRP3,SEC23A,ARHGDIA,RSRC2,PDGFB,KIAA1967,FAM92A,CCDC24 |
| mitogen-activated protein kinase kinase binding | BRAF,RAF1,PIN1,TAOK2,TRIB2,ACE,TRIB3,KSR1,MAP3K11,DLG1 |
| protein phosphatase type 2A regulator activity | PPP2R5EB,PPME1,PPP2R2C,PPP2R5C,SET,PPP2R5B,PPP2R5E,PPP2R3A,PPP2R2D,PPP2R1A |
| protein domain specific binding | KCTD13,WHRN,GABRR2,CNOT1,SHC4,XPO1,RAB6A,EZR,TRIM11,KPNB1 |
| protein phosphatase 2A binding | TRP53,ARPP19,CTTNBP2NL,GRIN3A,PPP2R4,AKT1,SMG5,STRN4,FOXO1,PPME1 |
Interacting Protein
IGBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGBP1.
PPP2CA;PPP4C
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References
- Onda, M; Inui, S; et al. Expression and chromosomal localization of the human alpha 4/IGBP1 gene, the structure of which is closely related to the yeast TAP42 protein of the rapamycin-sensitive signal transduction pathway. GENOMICS 46:373-378(1997).
