IFT52
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Official Full Name
IFT52 intraflagellar transport 52 homolog (Chlamydomonas) [ Homo sapiens ] -
Synonyms
intraflagellar transport 52 homolog (Chlamydomonas);15901;Ensembl:ENSG00000101052;intraflagellar transport protein 52 homolog;protein NGD5 homolog;NGD2;NGD5;CGI-53;C20orf9;dJ1028D15.1
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IFT52-14092H | Recombinant Human IFT52, His-tagged | E.coli | Human | His | 1-437a.a. | |
| IFT52-1432C | Recombinant Chicken IFT52 | Mammalian Cells | Chicken | His |
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| IFT52-2213R | Recombinant Rhesus monkey IFT52 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| IFT52-244Z | Recombinant Zebrafish IFT52 | Mammalian Cells | Zebrafish | His |
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| IFT52-5274HCL | Recombinant Human IFT52 293 Cell Lysate | HEK293 | Human | Non |
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| IFT52-2034R | Recombinant Rhesus Macaque IFT52 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| IFT52-2034R-B | Recombinant Rhesus Macaque IFT52 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| Ift52-3486M | Recombinant Mouse Ift52 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| IFT52-3954H | Recombinant Human IFT52 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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Involved Pathway
IFT52 involved in several pathways and played different roles in them. We selected most pathways IFT52 participated on our site, such as Assembly of the primary cilium,Hedgehog off state,Intraflagellar transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFT52 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Organelle biogenesis and maintenance | HSPB11,C11orf60,ARL3,RAB3IP,IFT-20,MRPL50,MRPS22,MRPL51,UNC119B,IFT74 |
| Signaling by Hedgehog | IFT88,INTU,GPR161,BBS13,GAS8,IQCE,SPOP,DZIP1,IFT172,KIF7 |
| Intraflagellar transport | IFT22,IFT172,IFT88,TTC30A2,DYNLRB1,TTC30B,IFT43,IFT46,DYF-1,TTC30A |
| Hedgehog off state | TTC21B,KIF7,OFD1,MKS1,WDR35,KIF3A,WDR19,BBS13,IFT172,TULP3 |
| Assembly of the primary cilium | MKS1,IFT74,FBF1,WDR35,SCLT1,CEP72,KIF17,CP110,WDR34,KIF3C |
| Signal Transduction | SHB,TAS2R13,APOC2,SPRY1,CSNK1G2,CRABP1B,PTPRUB,TAX1BP1B,WDR35,TAC1 |
Protein Function
IFT52 has several biochemical functions, for example, protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFT52 itself. We selected most functions IFT52 had, and list some proteins which have the same functions with IFT52. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein C-terminus binding | DDX1,FIGN,SP1,SDC1,CTBP1,SIRT1,VGLL1,ZBTB16,PPP2CA,ERCC6 |
Interacting Protein
IFT52 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFT52 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFT52.
Resources
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References
- Taschner, M; Kotsis, F; et al. Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly. JOURNAL OF CELL BIOLOGY 207:269-282(2014).
- Finetti, F; Patrussi, L; et al. Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system. JOURNAL OF CELL SCIENCE 127:1924-1937(2014).
