IFNβ
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Official Full Name
interferon beta 1, fibroblast -
Overview
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily, and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites and tumor cells. IFNs are produced by a wide variety of cells in response to the presence of dsRNA, a key indicator of viral infection via a pattern recognition receptor of the innate immune system Toll Like Receptor 3 (TLR 3), and in turn assists the immune response by inhibiting viral replication within host cells, activating natural killer cells and macrophages, increasing antigen presentation to lymphocytes, and inducing the resistance of host cells to viral infection. There are three major classes of IFNs according to the receptor type through which they signal, and the type I IFNs bind to a specific receptor complex known as the IFN-α receptor (IFNAR) consisting of IFNAR1 and IFNAR2 chains. -
Synonyms
IFNB1;interferon, beta 1, fibroblast;IFB;IFF;IFNB;MGC96956;interferon beta;IFN-beta
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Involved Pathway
IFNβ involved in several pathways and played different roles in them. We selected most pathways IFNβ participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNβ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
IFNβ has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by IFNβ itself. We selected most functions IFNβ had, and list some proteins which have the same functions with IFNβ. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
IFNβ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNβ here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNβ.
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