IFNA5
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Official Full Name
interferon, alpha 5 -
Overview
Interferon alpha-5 is a protein that in humans is encoded by the IFNA5 gene. -
Synonyms
IFNA5;interferon, alpha 5;interferon alpha-5;IFN alphaG;Interferon alpha 61;Interferon alpha G;LeIF G;IFN-alpha-5;interferon alpha-G;interferon alpha-61;INFA5;IFN-alphaG
Recombinant Proteins
- Human
- Mouse
- Rat
- HEK293
- E.coli
- HEK293F
- Human Cell
- Yeast
- Fc
- His
- His&GST
- Non
- Myc&DDK
Involved Pathway
IFNA5 involved in several pathways and played different roles in them. We selected most pathways IFNA5 participated on our site, such as Cytokine-cytokine receptor interaction,Regulation of autophagy,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ne thyroid disease | CD40,IFNA13,HLA-DQB1,HLA-DRA,HLA-F,HLA-DPA1,HLA-DMA,HLA-DMB,HLA-DRB3,HLA-A |
| Regulation of autophagy | ATG13,IFNA1,PIK3R4,IFNA8,IFNA6,ATG5,ATG12,ULK2,IFNA2,ATG4C |
| Autoi | IFNA4,IFNA12,FAS,HLA-DMB,HLA-DRB1,HLA-DRB5,HLA-DQA2,H2-AB1,IFNA13,HLA-B |
| Cytokine-cytokine receptor interaction | TNFRSF11B,LTB,TNFSF13,TNFRSF17,IFNAR2,IFNA13,IL15,CXCL13,TGFB2,TGFBR2 |
| Influenza A | PIK3CG,IFNA2,MAVS,ICAM1,IFNA14,IL6,IL18,HLA-DPA1,LOC780933,HLA-DMA |
| Hepatitis B | ATF4,TBK1,IKBKE,TLR4,SMAD3,FADD,PIK3R1,MAP3K1,EP300,HSPG2 |
| Measles | OAS1,CD28,CD209A,TLR4,Cd209g,IL6,IFNA7,CD46,NFKB1,CCNE2 |
| Hepatitis C | PIAS1,BRAF,IKBKG,TRAF3,CLDN2,IRF9,EIF2AK3,OAS1,NFKB1,PPARA |
| RIG-I-like receptor signaling pathway | TRAF2,RIPK1L,Ifna11,IFNW1,IFNB1,IRF3,IKBKG,IL12A,PIN1,CASP10 |
Protein Function
IFNA5 has several biochemical functions, for example, cytokine activity,cytokine receptor binding,type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA5 itself. We selected most functions IFNA5 had, and list some proteins which have the same functions with IFNA5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| type I interferon receptor binding | GM13285,IFNA12,IFNA6,IFNA13,Ifna15,IFNA1,IFNPHI3,IFNB,Ifna11,OSTN |
| cytokine activity | CTF1,IL15L,FASLG,TIMP1,IL6,IFNW1,IL15,SCGB3A1,NODAL,IL3 |
| cytokine receptor binding | Ifna11,IFNPHI2,IFNA14,IFNA3,IFNA21,MIF,IL17C,IFN-a,IL17A/F3,IFNPHI4 |
Interacting Protein
IFNA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA5.
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References
- Miterski, B; Jaeckel, S; et al. The interferon gene cluster: a candidate region for MS predisposition?. GENES AND IMMUNITY 1:37-44(1999).
- Cull, VS; Bartlett, EJ; et al. Type I interferon gene therapy protects against cytomegalovirus-induced myocarditis. IMMUNOLOGY 106:428-437(2002).
