IFNA21
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Official Full Name
interferon, alpha 21 -
Overview
This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus. -
Synonyms
IFNA21;interferon, alpha 21;interferon alpha-21;IFN alphaI;leukocyte interferon protein;Interferon alpha F;LeIF F;MGC126687;MGC126689;IFN-alpha-21;interferon alpha-F;leIF-F;IFN-alphaI
Recombinant Proteins
- Human
- E.coli
- Spf Chicken Eggs
- HEK293
- Yeast
- GST
- His
- Non
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IFNA21-617H | Recombinant Human IFNA21 Protein, His/GST-tagged | E.coli | Human | GST&His | Asp25~Glu189 | |
| IFNA21-140H | Recombinant Human Interferon, Alpha 21 | Spf Chicken Eggs | Human | Non |
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| IFNA21-41H | Recombinant Human Interferon, Alpha 21 | E.coli | Human | Non |
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| IFNA21-77H | Recombinant Human Interferon, Alpha 21 | E.coli | Human | Non |
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| IFNA21-5280HCL | Recombinant Human IFNA21 293 Cell Lysate | HEK293 | Human | Non |
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| IFNA21-076H | Recombinant Human IFNA21 Protein | E.coli | Human | 24-189 a.a. |
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| IFNA21-1424H | Recombinant Human IFNA21 Protein (24-189 aa), His-tagged | Yeast | Human | His | 24-189 aa |
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| IFNA21-3069H | Recombinant Human IFNA21 protein, His-tagged | E.coli | Human | His | 24-189aa |
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| IFNA21-3100H | Recombinant Human IFNA21 Protein (Asp25-Glu189), N-GST tagged | E.coli | Human | GST | Asp25-Glu189 |
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| IFNA21-6275H | Recombinant Human IFNA21 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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Involved Pathway
IFNA21 involved in several pathways and played different roles in them. We selected most pathways IFNA21 participated on our site, such as Cytokine-cytokine receptor interaction,Regulation of autophagy,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Jak-STAT signaling pathway | IL13,IFNW1,Il2,THPO,GHR,Il6ra,GH1,IL7,IL11RA,IL3 |
| Regulation of autophagy | BECN1,IFNA16,ATG16L1,IFNA14,ATG12,IFNA1,PRKAA2,INS2,IFNA5,IFNA17 |
| Herpes simplex infection | IFIT1,SRSF2B,PTPN11B,CCL5,IL12B,RNASEL,TRAF5,IKBKB,ARNTL,HLA-DQB1 |
| Influenza A | TMPRSS13,NXF3,HLA-DMA,NFKBIB,ACTB,IFN-a,HSPA6,MAPK3,PIK3R2,RSAD2 |
| Natural killer cell mediated cytotoxicity | TNFSF10,KLRC3,TNFRSF10B,NCR1,IFNAR2,PRKCG,FASLG,ICAM1,MAPK1,IFNA10 |
| Cytosolic DNA-sensing pathway | IKBKG,IFNA14,IFNPHI1,IL18,TMEM173,RIPK3,NFKB1,IFNA8,CXCL10,AIM2 |
| Hepatitis C | NR1H3,IFNA7,CLDN7,NRAS,PIK3CA,PIK3R2,RIPK1,TYK2,PPP2R2A,IFNA4 |
| Cytokine-cytokine receptor interaction | IFNG1-2,IL1B,CCL27B,XCL2,RELT,IFNGR2,KITLGA,ACVR1BA,LEPR,CXCL13 |
| Toll-like receptor signaling pathway | MAP2K6,IL12B,IL-8,SPP1,IRAK1,PIK3R2,IL8L1,FADD,CCL3L3,PIK3CD |
Protein Function
IFNA21 has several biochemical functions, for example, cytokine activity,cytokine receptor binding,type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA21 itself. We selected most functions IFNA21 had, and list some proteins which have the same functions with IFNA21. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| type I interferon receptor binding | IFNA12,IFNA14,IFNPHI1,Ifna11,IFNA2,IFNA17,IFNA8,IFNPHI2,IFNA16,GM13285 |
| cytokine activity | FAM3D,GPI,IL4,FAM3C,IL17F,IFNB1,TGFB1A,IFNA4,Ifnl2,IFN-a |
| cytokine receptor binding | IFNA12,IL17A/F2,IL17B,IFNW1,IFNPHI4,IFNA13,IL17A,IL17F,IFNPHI2,IL17A/F1 |
Interacting Protein
IFNA21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA21 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA21.
Resources
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References
- Guo, YL; Gao, MC; et al. Molecular cloning and characterization of a novel bovine IFN-epsilon. GENE 558:25-30(2015).
- Liu, R; Huang, DD; et al. Immunization with Recombinant SFTSV/NSs Protein Does Not Promote Virus Clearance in SFTSV-Infected C57BL/6J Mice. VIRAL IMMUNOLOGY 28:113-122(2015).
