ICMT
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Official Full Name
isoprenylcysteine carboxyl methyltransferase -
Overview
This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. -
Synonyms
ICMT;isoprenylcysteine carboxyl methyltransferase;protein-S-isoprenylcysteine O-methyltransferase;HSTE14;PCCMT;PPMT;protein S isoprenylcysteine O methyltransferase;1700008E11Rik;C80758;fcmt;Gm13095;MGC118506;OTTMUSG00000010406;ICMT_HUMAN;Isoprenylcysteine carboxylmethyltransferase;MGC39955;MGC95322;MST098;MSTP098;PCMT;Prenylated protein carboxyl methyltransferase;Prenylcysteine carboxyl methyltransferase;RP23-421E12.4;STE14;protein-S isoprenylcysteine O-methyltransferase
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ICMT-3832H | Recombinant Human ICMT protein, His-tagged | E.coli | Human | His | 87-213 aa | |
| ICMT-1443C | Recombinant Chicken ICMT | Mammalian Cells | Chicken | His |
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| ICMT-2389Z | Recombinant Zebrafish ICMT | Mammalian Cells | Zebrafish | His |
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| RFL13849OF | Recombinant Full Length Oryza Sativa Subsp. Indica Probable Protein-S-Isoprenylcysteine O-Methyltransferase(Icmt) Protein, His-Tagged | E.coli | Rice | His | Full L. Full Length (1-191) |
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| RFL16060RF | Recombinant Full Length Rat Protein-S-Isoprenylcysteine O-Methyltransferase(Icmt) Protein, His-Tagged | E.coli | Rat | His | Full L. Full Length (1-232) |
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| RFL31735OF | Recombinant Full Length Oryza Sativa Subsp. Japonica Probable Protein-S-Isoprenylcysteine O-Methyltransferase(Icmt) Protein, His-Tagged | E.coli | Rice | His | Full L. Full Length (1-191) |
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Involved Pathway
ICMT involved in several pathways and played different roles in them. We selected most pathways ICMT participated on our site, such as Terpenoid backbone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ICMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Terpenoid backbone biosynthesis | PMVK,FDPS,HMGCS2,IDI1,PDSS1,ACAT2,PCYOX1,PDSS2,MVDA,MVD |
Protein Function
ICMT has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ICMT itself. We selected most functions ICMT had, and list some proteins which have the same functions with ICMT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ICMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ICMT here. Most of them are supplied by our site. Hope this information will be useful for your research of ICMT.
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