HTATSF1
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Official Full Name
HIV-1 Tat specific factor 1 -
Overview
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene. -
Synonyms
HTATSF1;HIV-1 Tat specific factor 1;HIV TAT specific factor 1;HIV Tat-specific factor 1;TAT SF1;cofactor required for Tat activation of HIV-1 transcription;TAT-SF1;dJ196E23.2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HTATSF1-14000H | Recombinant Human HTATSF1, His-tagged | E.coli | Human | His | 1-350a.a. | |
| HTATSF1-11419Z | Recombinant Zebrafish HTATSF1 | Mammalian Cell | Zebrafish | His |
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| HTATSF1-5254H | Recombinant Human HTATSF1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HTATSF1-5669HF | Recombinant Full Length Human HTATSF1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 429 amino acids |
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Involved Pathway
HTATSF1 involved in several pathways and played different roles in them. We selected most pathways HTATSF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HTATSF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HTATSF1 has several biochemical functions, for example, nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HTATSF1 itself. We selected most functions HTATSF1 had, and list some proteins which have the same functions with HTATSF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | CCDC59,RBMX,DROSHA,MRPL21,C2orf15,SRSF7,ARCN1,ALDOA,RBMS1,PDCD11 |
| nucleotide binding | UBE2KA,NAIP6,KIF5AA,SFRS9,AKT2L,PTBP2A,ARF4A,SEPT9B,CHD6,TLK1A |
Interacting Protein
HTATSF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTATSF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HTATSF1.
CSNK2A1;SNRPB;EEF1D;SNRPN;SF3A2;FLYWCH1;Sf3a1;SRSF4;q81xc3_bacan;ZNF512B;FEZ1;midostaurin;ssdna_dtdc;Junb;ARRB2;SNW1;PYHIN1;ESR2
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References
- Reissmann, S; et al. Cell penetration: scope and limitations by the application of cell-penetrating peptides. JOURNAL OF PEPTIDE SCIENCE 20:760-784(2014).
- Kang, W; Marasco, WA; et al. Anti-tat Hutat2:Fc mediated protection against tat-induced neurotoxicity and HIV-1 replication in human monocyte-derived macrophages. JOURNAL OF NEUROINFLAMMATION 11:-(2014).
