HS6ST1

  • Official Full Name

    heparan sulfate 6-O-sulfotransferase 1
  • Overview

    The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms

    HS6ST1;heparan sulfate 6-O-sulfotransferase 1;HH15;HS6ST;heparan-sulfate 6-O-sulfotransferase 1;HS6ST-1;heparan-sulfate 6-sulfotransferase

Recombinant Proteins

  • Human
  • Chicken
  • Mouse
  • E.coli
  • CHO
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • E.coli expression system
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
HS6ST1-13947H Recombinant Human HS6ST1, GST-tagged E.coli Human GST C-term-54a.a.
HS6ST1-420H Active Recombinant Human HS6ST1, His-tagged CHO Human His 28-401 a.a.
HS6ST1-5056H Recombinant Human HS6ST1 Protein, GST-tagged Wheat Germ Human GST
HS6ST1-6052C Recombinant Chicken HS6ST1 Mammalian Cell Chicken His
HS6ST1-7863M Recombinant Mouse HS6ST1 Protein Mammalian Cell Mouse His
HS6ST1-5384HCL Recombinant Human HS6ST1 293 Cell Lysate HEK293 Human Non
HS6ST1-4326M Recombinant Mouse HS6ST1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
HS6ST1-4326M-B Recombinant Mouse HS6ST1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
RFL2466HF Recombinant Full Length Human Heparan-Sulfate 6-O-Sulfotransferase 1(Hs6St1) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-411)

    Involved Pathway

    HS6ST1 involved in several pathways and played different roles in them. We selected most pathways HS6ST1 participated on our site, such as Glycosaminoglycan biosynthesis - heparan sulfate / heparin, which may be useful for your reference. Also, other proteins which involved in the same pathway with HS6ST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycosaminoglycan biosynthesis - heparan sulfate / heparin B4GALT7,HS3ST3B1B,HS2ST1,HS2ST1A,HS3ST3A1,EXTL2,GLCEA,B3GAT3,B3GALT6,EXT1A

    Protein Function

    HS6ST1 has several biochemical functions, for example, heparan sulfate 6-O-sulfotransferase activity,sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HS6ST1 itself. We selected most functions HS6ST1 had, and list some proteins which have the same functions with HS6ST1. You can find most of the proteins on our site.

    Function Related Protein
    sulfotransferase activity CHST2,SULT2ST3,SULT3ST2,SULT6B1,CHST12A,SULT1ST4,SULT2ST2,HS2ST1A,HS6ST3B,SULT2ST1
    heparan sulfate 6-O-sulfotransferase activity HS3ST1L2,SULT1ST6,SULT1ST8,GAL3ST3,SULT1ST1,SULT6B1,SULT1ST5,SULT2ST2,HS3ST3L,SULT1ST3

    Interacting Protein

    HS6ST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HS6ST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HS6ST1.

    Resources

    Research Area

    Proteoglycan Regulators

    References

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