HPX
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Official Full Name
hemopexin -
Overview
This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. -
Synonyms
HPX;hemopexin;Beta 1B glycoprotein;Beta-1B-glycoprotein;FLJ56652;HEMO;HEMO_HUMAN;HX;OTTHUMP00000164583
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Rat
- Zebrafish
- Human Plasma
- HEK293
- C-His
- E.coli
- Mammalian Cell
- Human
- Wheat Germ
- Human Cell
- HEK293T
- Human Serum or Plasma
- In Vitro Cell Free System
- Yeast
- Rat Serum
- Non
- His
- GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
HPX involved in several pathways and played different roles in them. We selected most pathways HPX participated on our site, such as Binding and Uptake of Ligands by Scavenger Receptors,Scavenging of heme from plasma,Vesicle-mediated transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with HPX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Scavenging of heme from plasma | NFX1,HP,CD163,LOC479668,AMBP |
| Binding and Uptake of Ligands by Scavenger Receptors | LOC479668,COL1A2,HYOU1,HSPH1,IGLC2,IGKC,CD163,STAB2,Alb,COL3A1 |
| Vesicle-mediated transport | TBC1D8B,TGOLN2,SH3D19,TRAPPC3,YIPF6,AMBP,HSPH1,GJA4,COPE,MIA3 |
Protein Function
HPX has several biochemical functions, for example, heme transporter activity,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HPX itself. We selected most functions HPX had, and list some proteins which have the same functions with HPX. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZNF143B,NT5DC1,TRIM2A,ZNF398,ZNF396,IRF2BP1,LOXL2B,ZFP524,ZNF317,ZFP428 |
| heme transporter activity | ABCG2,HRG-1,FLVCR1,MFSD7C,SLC48A1A,ABCB7,SLC48A1B,SLC48A1,MFSD7B |
| protein binding | RARG,AHCYL1,TSPAN2,MSH5,WBSCR27,DDX17,BLNK,PHF23,E2F4,TLR2 |
Interacting Protein
HPX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPX here. Most of them are supplied by our site. Hope this information will be useful for your research of HPX.
GLUD1;TP63;LTN1;ALB
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References
- Iwao, Y; Shiga, K; et al. The need of MMP-2 on the sperm surface for Xenopus fertilization: Its role in a fast electrical block to polyspermy. MECHANISMS OF DEVELOPMENT 134:80-95(2014).
- Peng, HY; Jiao, Y; et al. Magnetic quantitative analysis for multiplex glycoprotein with polymer-based elemental tags. JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY 29:1112-1119(2014).
