HPS3
-
Official Full Name
Hermansky-Pudlak syndrome 3 -
Overview
This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined. -
Synonyms
HPS3;Hermansky-Pudlak syndrome 3;Hermansky-Pudlak syndrome 3 protein;SUTAL;Cocoa;DKFZp686F0413;FLJ22704;Hermansky Pudlak syndrome 3;Hermansky Pudlak syndrome 3 protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HPS3-13926H | Recombinant Human HPS3, GST-tagged | E.coli | Human | GST | C-term-418a.a. | |
| HPS3-5015H | Recombinant Human HPS3 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| HPS3-7790Z | Recombinant Zebrafish HPS3 | Mammalian Cell | Zebrafish | His |
|
|
| HPS3-5396HCL | Recombinant Human HPS3 293 Cell Lysate | HEK293 | Human | Non |
|
|
| HPS3-3630HF | Recombinant Full Length Human HPS3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 372 amino acids |
|
Involved Pathway
HPS3 involved in several pathways and played different roles in them. We selected most pathways HPS3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HPS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HPS3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by HPS3 itself. We selected most functions HPS3 had, and list some proteins which have the same functions with HPS3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
HPS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HPS3.
Resources
Related Services
Related Products
References
- Gimelli, G; Giorda, R; et al. A large analphoid invdup(3)(q22.3qter) marker chromosome characterized by array-CGH in a child with malformations, mental retardation, ambiguous genitalia and Blaschko's lines. EUROPEAN JOURNAL OF MEDICAL GENETICS 50:264-273(2007).
- Helip-Wooley, A; Westbroek, W; et al. Association of the Hermansky-Pudlak syndrome type-3 protein with clathrin. BMC CELL BIOLOGY 6:-(2005).
