HOXB1

  • Official Full Name

    homeobox B1

  • Overview

    This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription;factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar;homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes;arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.

  • Synonyms

    HOXB1;homeobox B1;homeo box B1 , HOX2, HOX2I;homeobox protein Hox-B1;Homeo box 2I;Homeo box B1;Homeobox 2I;Homeobox protein Hox B1;Homeobox protein Hox-2I;Homeobox protein HoxB1;Homeobox2I;HomeoboxB1;HOX 2;Hox 2.9;HOX 2I;HOX B1;HOX2;Hox2.9;HOX2I;HOXB 1;HOXB1 protein;HXB1_HUMAN;MGC116843;MGC116844;MGC116845;OTTHUMP00000217086;Hox-2.9

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
HOXB1-13895H Recombinant Human HOXB1, GST-tagged E.coli Human GST 1-168a.a.
HOXB1-2131R Recombinant Rhesus monkey HOXB1 Protein, His-tagged Mammalian Cells Rhesus macaque His
HOXB1-3616C Recombinant Chicken HOXB1 Mammalian Cells Chicken His
HOXB1-4953H Recombinant Human HOXB1 Protein, GST-tagged Wheat Germ Human GST
HOXB1-810HCL Recombinant Human HOXB1 cell lysate Human Non
Hoxb1-1155M Recombinant Mouse Hoxb1 Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc
HOXB1-1897H Recombinant Human HOXB1 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
HOXB1-1952R Recombinant Rhesus Macaque HOXB1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
HOXB1-1952R-B Recombinant Rhesus Macaque HOXB1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
HOXB1-2272H Recombinant Human HOXB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
HOXB1-3715HF Recombinant Full Length Human HOXB1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 235 amino acids

    Involved Pathway

    HOXB1 involved in several pathways and played different roles in them. We selected most pathways HOXB1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Signaling pathways regulating pluripotency of stem cells SMAD5,WNT16,LEFTY2,STAT3,MAPK1,SMAD3,HAND1,BMPR1B,PIK3R3,BMI1

    Protein Function

    HOXB1 has several biochemical functions, for example, DNA binding,protein domain specific binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXB1 itself. We selected most functions HOXB1 had, and list some proteins which have the same functions with HOXB1. You can find most of the proteins on our site.

    Function Related Protein
    protein domain specific binding HIST2H4,HOMER2,TH,EZR,SHC4,MECP2,HIST2H4A,ICAL1,NCK1,ICA1L
    sequence-specific DNA binding HOXA13,NKX3,SOX14,RX2,ELF2,FOXD2,SOX21B,TCF7L1A,NKX2.5,SALL4
    DNA binding RX2,NFATC2,HNF1BA,BLM,APEX1,NUSAP1,ERG,FOXO1B,ESRRA,CREBZF

    Interacting Protein

    HOXB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXB1.

    PBX1

    Resources

    Research Area

    Neural Stem Cell Transcription Factors
    Neural Stem Cell Markers

    References

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