HOXA11
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Official Full Name
homeobox A11 -
Overview
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008] -
Synonyms
HOXA11;homeobox A11;HOX1;HOX1I;homeobox protein Hox-A11;homeo box 1I;homeobox protein HOXA11;homeobox protein Hox-1I
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- His&GST
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOXA11-095H | Recombinant Human HOXA11 Protein, GST-HIS-tagged | E.coli | Human | His&GST |
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| HOXA11-4940H | Recombinant Human HOXA11 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HOXA11-6187C | Recombinant Chicken HOXA11 | Mammalian Cell | Chicken | His |
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| HOXA11-7786M | Recombinant Mouse HOXA11 Protein | Mammalian Cell | Mouse | His |
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| HOXA11-5428HCL | Recombinant Human HOXA11 293 Cell Lysate | HEK293 | Human | Non |
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| HOXA11-3709HF | Recombinant Full Length Human HOXA11 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 313 amino acids |
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| HOXA11-4276M | Recombinant Mouse HOXA11 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HOXA11-4276M-B | Recombinant Mouse HOXA11 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HOXA11 involved in several pathways and played different roles in them. We selected most pathways HOXA11 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXA11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transcriptional misregulation in cancer | ETV1,BCL6,SIX4,CCNT1,BCL2A1,TP53,GOLPH3,FEV,DOT1L,FCGR1A |
Protein Function
HOXA11 has several biochemical functions, for example, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXA11 itself. We selected most functions HOXA11 had, and list some proteins which have the same functions with HOXA11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | ELF2B,ZNF831,NEUROG2,ESRRA,TP63,FOXC1,POU3F2A,CREB5,ELF2A,HNF1B |
Interacting Protein
HOXA11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXA11 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXA11.
PGBD3
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