HNRNPUL1
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Official Full Name
heterogeneous nuclear ribonucleoprotein U-like 1 -
Overview
This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding different isoforms have been found for this gene. Additional variants have also been found, but their full-length natures have not been determined. This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This;protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA;transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding;different isoforms have been found for this gene. Additional variants have also been found, but their full-length;natures have not been determined. -
Synonyms
HNRNPUL1;heterogeneous nuclear ribonucleoprotein U-like 1;HNRPUL1;heterogeneous nuclear ribonucleoprotein U-like protein 1;E1B 55kDa associated protein 5;E1B AP5;E1BAP5;FLJ12944;fk45c03;wu:fb53d10;Adenovirus early region 1B associated protein 5;E130317O14Rik;E1B 55 kDa associated protein 5;fb53d10;MGC36621;MGC78330;wu:fk45c03;zgc:85971;E1B-55kDa-associated protein 5;E1B-55 kDa-associated protein 5;adenovirus early region 1B-associated protein 5;E1B-AP5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HNRNPUL1-13877H | Recombinant Human HNRNPUL1, GST-tagged | E.coli | Human | GST | 1-227a.a. | |
| HNRNPUL1-12464Z | Recombinant Zebrafish HNRNPUL1 | Mammalian Cell | Zebrafish | His |
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| HNRNPUL1-7770M | Recombinant Mouse HNRNPUL1 Protein | Mammalian Cell | Mouse | His |
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| HNRNPUL1-805HCL | Recombinant Human HNRNPUL1 cell lysate | Human | Non |
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| HNRNPUL1-4265M | Recombinant Mouse HNRNPUL1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HNRNPUL1-4265M-B | Recombinant Mouse HNRNPUL1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HNRNPUL1 involved in several pathways and played different roles in them. We selected most pathways HNRNPUL1 participated on our site, such as Gene Expression,Influenza A,Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPUL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Influenza A | HLA-DMA,HLA-DMB,SOCS3,IFNA1,IL1A,MAPK9,PYCARD,IFNA14,CXCL10,LOC100033925 |
| Gene Expression | ESR2A,C22orf28,VDRB,TSEN54,IGF2BP2,SPCS3,FAUB,ZNF500,C14orf166,PEAK1 |
| mRNA Splicing - Major Pathway | HNRNPA0B,PRPF8,HNRNPA2B1,RBM5,HNRNPR,HNRNPL,SF3B4,PTBP1B,HNRNPA0L,CD2BP2 |
| Processing of Capped Intron-Containing Pre-mRNA | HNRNPA0B,SF3B2,CSTF3,WTAP,METTL3,SLBP,CD2BP2,YBX1,RNPS1,PTBP1 |
| mRNA Splicing | RNPC3,HNRNPD,TTC6,HNRNPA0L,PTBP1A,HNRNPA2B1,HNRNPH1L,HNRNPA0B,SFRS3A,HNRNPA0 |
Protein Function
HNRNPUL1 has several biochemical functions, for example, RNA binding,enzyme binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPUL1 itself. We selected most functions HNRNPUL1 had, and list some proteins which have the same functions with HNRNPUL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enzyme binding | P4HB,PHKG2,AXIN1,ATXN10,Txn1,IL6R,DDX5,PRKCE,HIF1A,RARA |
| protein binding | FBXO34,RING1,PEX12,BAI3,BCL2L10,PEX13,CD97,CEP57L1,GLIS2,PAWR |
| poly(A) RNA binding | TAF15,ADAR,NCBP2,PA2G4,POLR2A,OASL1,PTBP2,ERAL1,AHNAK,PABPC1 |
| RNA binding | HNRNPA1L2,DPPA5A,SMN2,MIF4GDA,EXOSC1,NUFIP2,EIF4E3,D19BWG1357E,PPARGC1A,MSI1 |
Interacting Protein
HNRNPUL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPUL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPUL1.
TP53;WWP2;HNRNPF
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References
- Yamazaki, F; Kim, HH; et al. pY RNA1-s2: A Highly Retina-Enriched Small RNA That Selectively Binds to Matrin 3 (Matr3). PLOS ONE 9:-(2014).
- Hong, ZH; Jiang, J; et al. The Role of hnRPUL1 Involved in DNA Damage Response Is Related to PARP1. PLOS ONE 8:-(2013).
