HNRNPR

  • Official Full Name

    heterogeneous nuclear ribonucleoprotein R

  • Overview

    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

  • Synonyms

    HNRNPR;heterogeneous nuclear ribonucleoprotein R;HNRPR;hnRNP R;hnRNP-R

Recombinant Proteins

  • Zebrafish
  • Chicken
  • Human
  • Mouse
  • Mammalian Cells
  • Wheat Germ
  • Insect Cells
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Fc
  • Non
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
HNRNPR-12598Z Recombinant Zebrafish HNRNPR Mammalian Cells Zebrafish His
HNRNPR-1454C Recombinant Chicken HNRNPR Mammalian Cells Chicken His
HNRNPR-4906H Recombinant Human HNRNPR Protein, GST-tagged Wheat Germ Human GST
HNRNPR-8649H Recombinant Human HNRNPR, His-GST tagged Insect Cells Human Fc&His 2-636 a.a.
HNRNPR-001HCL Recombinant Human HNRNPR cell lysate Insect Cells Human Non
HNRNPR-1767H Recombinant Human HNRNPR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
HNRNPR-1845H Recombinant Human HNRNPR Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
HNRNPR-3238H Recombinant Human HNRNPR protein(Ala2-Lys636), His&GST-tagged Insect Cells Human GST&His Ala2-Lys636
Hnrnpr-3421M Recombinant Mouse Hnrnpr Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
HNRNPR-3618HF Recombinant Full Length Human HNRNPR Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 633 amino acids
HNRNPR-5385H Recombinant Human HNRNPR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc

    Involved Pathway

    HNRNPR involved in several pathways and played different roles in them. We selected most pathways HNRNPR participated on our site, such as Gene Expression,Processing of Capped Intron-Containing Pre-mRNA,mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Processing of Capped Intron-Containing Pre-mRNA PTBP1B,CLP1,CCAR1,BCAS2,SF3B2,HNRNPH1L,SRSF11,RNPS1,U2AF2,RNPC3
    Gene Expression NR5A1A,NR1D2B,ZNF43,PHF19,COX4I1,ZNF543,ZNF19,ELL,PTBP1,ZNF606
    mRNA Splicing - Major Pathway HNRNPA0,HNRNPA0A,BCAS2,HNRNPA0L,SFRS3A,SF3B4,PCBP2,HNRPL,HNRNPA2B1,SF3A3
    mRNA processing LOC100862398,SREK1,SFRS3A,QK,DDX39,HNRNPABA,RBM39A,PTBP1,CLK1,PRPF8
    mRNA Splicing HNRNPL,HNRNPA0,SNRNP25,YBX1,SNRNP35,SF3A1,DNAJC8,PDCD7,HNRNPH1L,PTBP1A

    Protein Function

    HNRNPR has several biochemical functions, for example, RNA binding,nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPR itself. We selected most functions HNRNPR had, and list some proteins which have the same functions with HNRNPR. You can find most of the proteins on our site.

    Function Related Protein
    nucleotide binding PRKG1A,ABT1,PUF60A,NME2B.1,KIF20B,Fert2,NXF2,STK25B,ARL3L1,MATR3L
    protein binding F3,COA3,SNX32,ZNF79,ROPN1,FDXR,LCAT,ZC3H10,SOX4,CCDC170
    poly(A) RNA binding GTL3,RPL30,SSRP1,PTBP1,GRN,UBC,ELAVL1,CSTF2,RPL7L1,RPL5A
    RNA binding EIF4EA,HNRNPK,C1D,KHDRBS1,DIS3,CRNKL1,HNRNPL2,MRPL3,IGHMBP2,HNRNPA2B1

    Interacting Protein

    HNRNPR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPR here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPR.

    YBX1;PRMT1;KHDRBS2;ssrna_cg;ESR1;TOP1

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