HIST1H1B

  • Official Full Name

    histone cluster 1, H1b

  • Overview

    Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

  • Synonyms

    HIST1H1B;histone cluster 1, H1b;H1 histone family, member 5 , H1F5, histone 1, H1b;histone H1.5;H1.5;H1;H1 histone family member 5;H15 HUMAN;H15_HUMAN;H1F5;Histone 1 H1b;Histone cluster 1 H1b;Histone H1a;MGC126630;MGC126632;histone 1, H1b;H1 histone family, member 5;H1B

Recombinant Proteins

  • Rhesus macaque
  • Rat
  • Mouse
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • Avi&Fc&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
HIST1H1B-2086R Recombinant Rhesus monkey HIST1H1B Protein, His-tagged Mammalian Cells Rhesus macaque His
HIST1H1B-2849R Recombinant Rat HIST1H1B Protein Mammalian Cells Rat His
HIST1H1B-7643M Recombinant Mouse HIST1H1B Protein Mammalian Cells Mouse His
HIST1H1B-5554HCL Recombinant Human HIST1H1B 293 Cell Lysate HEK293 Human Non
HIST1H1B-1907R Recombinant Rhesus Macaque HIST1H1B Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
HIST1H1B-1907R-B Recombinant Rhesus Macaque HIST1H1B Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
HIST1H1B-2504R Recombinant Rat HIST1H1B Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
HIST1H1B-2504R-B Recombinant Rat HIST1H1B Protein Pre-coupled Magnetic Beads HEK293 Rat
HIST1H1B-4174M Recombinant Mouse HIST1H1B Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
HIST1H1B-4174M-B Recombinant Mouse HIST1H1B Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    HIST1H1B involved in several pathways and played different roles in them. We selected most pathways HIST1H1B participated on our site, such as Activation of DNA fragmentation factor,Apoptosis,Apoptosis induced DNA fragmentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular Senescence TERF2IP,TNIK,CEBPB,CDKN2C,SUZ12,HIST1H1C,SUZ12A,LMNB1,CDKN2B,E2F3
    Apoptotic execution phase HMGB2A,SATB1,PKP1,CTNNB1,CLSPN,DNM1L,SPNA2,HIST1H1D,CASP6L2,PLEC
    Activation of DNA fragmentation factor HIST1H1E,HMGB2A,HMGB2,HIST1H1C,DFFA,HIST1H1A,H1F0,HIST1H1D
    Formation of Senescence-Associated Heterochromatin Foci (SAHF) HIST1H1E,EP400,H1F0,CABIN1,ASF1A,HIST1H1C,HIST1H1A,UBN1,HIRA,HMGA1-RS1
    Cellular responses to stress TNIK,CDKN2D,CDKN2B,TXNRD2,PRDX2,NUP35,WDR45L,GABARAPL2,HSPA14,TERF2IP
    Apoptosis induced DNA fragmentation HMGB2,HIST1H1D,HIST1H1E,H1F0,HIST1H1A,HMGB2A,DFFA,HIST1H1C
    Apoptosis MAP3K14,IRF1B,IRF6,IRAK4,IL1A,IL3RA,TRP53,BIRC3,FAS,AKT2L
    DNA Damage/Telomere Stress Induced Senescence RAD50,POT1A,TERF1,ACD,TERF2,HMGA1,TINF2,HTATIP,HIST1H1D,UBN1

    Protein Function

    HIST1H1B has several biochemical functions, for example, chromatin DNA binding,histone deacetylase binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H1B itself. We selected most functions HIST1H1B had, and list some proteins which have the same functions with HIST1H1B. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding SNRNP200,CSTF2T,PUS1,BICC1,HDGF,CPNE3,FAM98A,SUGP1,HSPA9,NMD3
    histone deacetylase binding ANKRA2,SRF,NR2C1,SP2,KAT2B,PRDM1,HDAC4,GMNN,YWHAB,MAPK8
    chromatin DNA binding H1F0,PRDM14,INSM1B,GATA1,FOXC2,RELA,GRHL1,H2AFY,SMAD3,PER1

    Interacting Protein

    HIST1H1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H1B here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H1B.

    VCAM1;ssrna_ug

    Resources

    Research Area

    H1 Family

    References

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