HIP1R

  • Official Full Name

    huntingtin interacting protein 1 related

  • Overview

    Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.

  • Synonyms

    HIP1R;huntingtin interacting protein 1 related;HIP3;HIP12;ILWEQ;huntingtin-interacting protein 1-related protein;HIP-12;HIP1-related protein;huntingtin interacting protein 12;huntingtin-interacting protein 12

Recombinant Proteins

  • Human
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • GST
  • His
  • Myc&DDK
  • His&T7
  • Non
  • His&Fc&Avi
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
HIP1R-13784H Recombinant Human HIP1R, GST-tagged E.coli Human GST 266-615a.a.
HIP1R-2363C Recombinant Chicken HIP1R Mammalian Cell Chicken His
HIP1R-29320TH Recombinant Human HIP1R, His-tagged E.coli Human His 729-876 a.a.
HIP1R-29H Recombinant Human HIP1R, GST-tagged Wheat Germ Human GST 1-1068 a.a.
HIP1R-30H Recombinant Human HIP1R, MYC/DDK-tagged HEK293 Human Myc&DDK
HIP1R-7635M Recombinant Mouse HIP1R Protein Mammalian Cell Mouse His
HIP1R-7857H Recombinant Human HIP1R protein, His & T7-tagged E.coli Human His&T7 Ser771~Ala1012
HIP1R-789HCL Recombinant Human HIP1R cell lysate Human Non
HIP1R-3232H Recombinant Human HIP1R Protein (Ser771-Ala1012), N-His tagged E.coli Human His Ser771-Ala1012
Hip1r-3399M Recombinant Mouse Hip1r Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
HIP1R-4168M Recombinant Mouse HIP1R Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
HIP1R-4168M-B Recombinant Mouse HIP1R Protein Pre-coupled Magnetic Beads HEK293 Mouse
HIP1R-4385H Recombinant Human HIP1R Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
HIP1R-560HF Recombinant Full Length Human HIP1R Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 1068 amino acids
HIP1R-9016HFL Recombinant Full Length Human HIP1R, Flag-tagged Mamanlian cells Human Flag Full L.

    Involved Pathway

    HIP1R involved in several pathways and played different roles in them. We selected most pathways HIP1R participated on our site, such as Clathrin derived vesicle budding,Golgi Associated Vesicle Biogenesis,Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIP1R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Golgi Associated Vesicle Biogenesis NECAP1,BLOC1S3,PICALMA,SNAPIN,YIPF6,BLOC1S4,CPD,DTNBP1,BLOC1S1,NAPAB
    Vesicle-mediated transport SNAPIN,TGOLN2,COPE,HYOU1,GJA4,TRAPPC6BL,TBC1D8B,PICALMB,STAB2,TRAPPC9
    trans-Golgi Network Vesicle Budding YIPF6,CLVS2,BLOC1S1,TPD52,SNX9,DNASE2,GAK,HIP1RB,AP4B1,SH3D19
    Membrane Trafficking TRAPPC2L,DNASE2,BLOC1S4,NAPB,NSFB,PICALMB,TRAPPC6BL,TRAPPC6B,LMAN2L,DAB2
    Clathrin derived vesicle budding ARF1,FTH1A,AP3S1,YIPF6,HIP1RB,APPA,DTNBP1,TPD52L1,CNO,NAPAA

    Protein Function

    HIP1R has several biochemical functions, for example, actin binding,clathrin binding,phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIP1R itself. We selected most functions HIP1R had, and list some proteins which have the same functions with HIP1R. You can find most of the proteins on our site.

    Function Related Protein
    clathrin binding SCLT1,SYT5A,SNAP91,SMAP1,HIP1RB,SYT13,AFTPH,DOC2B,LRRK2,TOM1L1
    actin binding KLHL3,Fert2,MYH9A,CAPGB,PARVA,PARVAA,PARVG,MSNA,MPRIP,CAPZA2
    phosphatidylinositol binding SNX12,RAG2,SNX9B,ITPR3,HIP1RB,ING2,SNX1B,SNX13,SNX1A,SNX27
    protein binding CD84,ARF4,TNFSF13B,SYCE2,MKNK2,VPS41,RRM2B,ETF1,PHF8,NCKAP1

    Interacting Protein

    HIP1R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIP1R here. Most of them are supplied by our site. Hope this information will be useful for your research of HIP1R.

    q53hg7_human;UBA1;UBE2N;UBE2V1;Map3k1;pi3p;Sec24c;GAK;CLTB;VCAM1;MYH9;CAPZA2;CD81;Actb

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