HELQ
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Official Full Name
helicase, POLQ-like -
Overview
HEL308 is a single-stranded DNA-dependent ATPase and DNA helicase (Marini and Wood, 2002 (PubMed 11751861)). -
Synonyms
HELQ;helicase, POLQ-like;helicase POLQ-like;Hel308;HEL308 protein;Helicase, POLQ like;Mus308 like helicase;POLQ like helicase;OTTHUMP00000160977;OTTHUMP00000219793;POLQ-like helicase;DNA helicase HEL308;mus308-like helicase
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Wheat Germ
- Mammalian Cell
- In Vitro Cell Free System
- HEK293
- E.coli
- GST
- His
- Non
- His&Fc&Avi
- N-His&C-Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HELQ-4681H | Recombinant Human HELQ Protein, GST-tagged | Wheat Germ | Human | GST |
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| HELQ-7568M | Recombinant Mouse HELQ Protein | Mammalian Cell | Mouse | His |
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| HELQ-8379Z | Recombinant Zebrafish HELQ | Mammalian Cell | Zebrafish | His |
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| HELQ-778HCL | Recombinant Human HELQ cell lysate | Human | Non |
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| HELQ-3464HF | Recombinant Full Length Human HELQ Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 272 amino acids |
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| HELQ-4118M | Recombinant Mouse HELQ Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HELQ-4118M-B | Recombinant Mouse HELQ Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| HELQ-5766H | Recombinant Human HELQ protein, His&Myc-tagged | E.coli | Human | N-His&C-Myc | 350-726aa |
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Involved Pathway
HELQ involved in several pathways and played different roles in them. We selected most pathways HELQ participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HELQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HELQ has several biochemical functions, for example, ATP binding,helicase activity,nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HELQ itself. We selected most functions HELQ had, and list some proteins which have the same functions with HELQ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| helicase activity | ZRANB3,MCM8,DDX3,BAT1,GTF2F2A,MOV10B.2,SMARCAL1,ERCC6L,SUPV3L1,DHX58 |
| nucleic acid binding | RBM14B,JAZF1A,SNRNP27,C19orf6,RBM4.1,ENOX2,ZBTB12.2,SSX3,DBF4B,SETD1B |
| ATP binding | RPS6KA3,PRKCBB,UBE2W,PFKFB3,PIK3C2A,PDPK1,ACACA,TTF2,CSNK1G2A,STK32B |
Interacting Protein
HELQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HELQ here. Most of them are supplied by our site. Hope this information will be useful for your research of HELQ.
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Resources
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References
- Babron, MC; Kazma, R; et al. Genetic variants in DNA repair pathways and risk of upper aerodigestive tract cancers: combined analysis of data from two genome-wide association studies in European populations. CARCINOGENESIS 35:1523-1527(2014).
- Luebben, SW; Kawabata, T; et al. Helq acts in parallel to Fancc to suppress replication-associated genome instability. NUCLEIC ACIDS RESEARCH 41:10283-10297(2013).
