HCRTR1

  • Official Full Name

    hypocretin (orexin) receptor 1

  • Overview

    The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.

  • Synonyms

    HCRTR1;hypocretin (orexin) receptor 1;orexin receptor type 1;OX1R;ox1-R;ox-1-R;orexin receptor 1;orexin receptor-1;hypocretin receptor 1;hypocretin receptor-1;hypocretin receptor type 1

Recombinant Proteins

  • Rat
  • Human
  • Mouse
  • Mus musculus
  • Bovine
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • E.coli
  • In Vitro Cell Free System
  • Yeast
  • His
  • Non
  • GST
  • His&Flag
  • His&Myc
  • His&Fc&Avi
  • His&SUMO
Cat.# Product name Source (Host) Species Tag Protein Length Price
HCRTR1-2811R Recombinant Rat HCRTR1 Protein Mammalian Cells Rat His
HCRTR1-4633H Recombinant Human HCRTR1 Protein Wheat Germ Human Non
HCRTR1-4634H Recombinant Human HCRTR1 Protein, GST-tagged Wheat Germ Human GST
HCRTR1-7523M Recombinant Mouse HCRTR1 Protein Mammalian Cells Mouse His
HCRTR1-5609HCL Recombinant Human HCRTR1 293 Cell Lysate HEK293 Human Non
HCRTR1-0696H Recombinant Human HCRTR1 Protein (M1-Q246, K288-L380), Flag, 10×His tagged Mammalian Cells Human His&Flag M1-Q246, K288-L380
HCRTR1-1124HFL Recombinant Human HCRTR1 protein, His&Flag-tagged HEK293 Human His&Flag 1-425 aa
HCRTR1-12H Recombinant Human HCRTR1 Protein (M1-Q246, K288-L380), N-Flag and C-10×His-tagged Mammalian Cells Human His&Flag M1-Q246, K288-L380
HCRTR1-2463H Recombinant Human HCRTR1 Protein (1-46 aa), His-Myc-tagged E.coli Human His&Myc 1-46 aa
HCRTR1-2466R Recombinant Rat HCRTR1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
HCRTR1-2466R-B Recombinant Rat HCRTR1 Protein Pre-coupled Magnetic Beads HEK293 Rat
HCRTR1-294H Recombinant Human HCRTR1 Full Length Transmembrane protein(Nanodisc) HEK293 Human Non Full L.
HCRTR1-3571HF Recombinant Full Length Human HCRTR1 Protein In Vitro Cell Free System Human Full L. 1,210 amino acids
HCRTR1-3608HF Recombinant Full Length Human HCRTR1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 425 amino acids
HCRTR1-4085M Recombinant Mouse HCRTR1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
HCRTR1-4085M-B Recombinant Mouse HCRTR1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
HCRTR1-5423H Recombinant Human HCRTR1 protein, His-sumostar-tagged Yeast Human His&SUMO 1-46aa
RFL29228RF Recombinant Full Length Rat Orexin Receptor Type 1(Hcrtr1) Protein, His-Tagged E.coli Rat His Full L. Full Length (1-416)
RFL32796MF Recombinant Full Length Mouse Orexin Receptor Type 1(Hcrtr1) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length (1-416)
RFL35175BF Recombinant Full Length Bovine Orexin Receptor Type 1(Hcrtr1) Protein, His-Tagged E.coli Bovine His Full L. Full Length (1-425)
RFL9729HF Recombinant Full Length Human Orexin Receptor Type 1(Hcrtr1) Protein, His-Tagged E.coli Human His Full L. Full Length (1-425)

    Involved Pathway

    HCRTR1 involved in several pathways and played different roles in them. We selected most pathways HCRTR1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCRTR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction GRIN1,EDNRB2,NPY7R,TRHRB,GRIA3,GRPR,TAAR1B,GRM1,CSH,GRM7

    Protein Function

    HCRTR1 has several biochemical functions, for example, G-protein coupled receptor activity,neuropeptide receptor activity,orexin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HCRTR1 itself. We selected most functions HCRTR1 had, and list some proteins which have the same functions with HCRTR1. You can find most of the proteins on our site.

    Function Related Protein
    neuropeptide receptor activity NPFFR2.1,NPFFR1L2,NPBWR1,KISS1RB,NMUR1,KISS1RA,NPFFR1L1,SORCS3,SORCS2,NPFFR2
    peptide binding ANG,ERAP2,TRHDE,CTSB,MAS1,FNTB,CRHBP,NPFFR2,CCKAR,RPS6KB2
    G-protein coupled receptor activity RXFP2B,GLP2R,HCAR1-2,OR52B2,GPR55A,PRLH2R,OLFCG2,RXFP3.2B,GPR183,OR2H1
    orexin receptor activity HCRTR2
    peptide hormone binding GIPR,SLC40A1,INHBA,PTH1RA,OXTR,ECE1,AGTR1A,MAS1,GALR3,MC3R

    Interacting Protein

    HCRTR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCRTR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HCRTR1.

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