HCAR3
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Official Full Name
hydroxycarboxylic acid receptor 3 -
Overview
Niacin receptor 2, also known as NIACR2 or GPR109B, is a protein which in humans is encoded by the NIACR2 gene. -
Synonyms
HCAR3;hydroxycarboxylic acid receptor 3;G protein coupled receptor 109B , GPR109B;HCA3;HM74;G protein coupled receptor 109B;G protein coupled receptor HM74;G protein coupled receptor HM74B;GPR 109B;GPR109;GPR109B;HM 74;Niacin receptor 2;NIACR2;Nicotinic acid receptor 2;Probable G protein coupled receptor HM74;Puma g;PUMAG;GTP-binding protein;putative chemokine receptor;G protein-coupled receptor 109B;G-protein coupled receptor 109B;G-protein coupled receptor HM74;G-protein coupled receptor HM74B;hydroxy-carboxylic acid receptor 3;Puma-g
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HCAR3-737HCL | Recombinant Human HCAR3 cell lysate | Human | Non |
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| HCAR3-5167H | Recombinant Human HCAR3 Protein | Wheat Germ | Human | Non |
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| HCAR3-5168H | Recombinant Human HCAR3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HCAR3-5563HF | Recombinant Full Length Human HCAR3 Protein | In Vitro Cell Free System | Human | Full L. 372 amino acids |
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| HCAR3-5565HF | Recombinant Full Length Human HCAR3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 387 amino acids |
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| RFL20598HF | Recombinant Full Length Human Hydroxycarboxylic Acid Receptor 3(Hcar3) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-387) |
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Involved Pathway
HCAR3 involved in several pathways and played different roles in them. We selected most pathways HCAR3 participated on our site, such as cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCAR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| cAMP signaling pathway | FXYD1,PLD2,BDNF,SLC9A1,GRIN3A,CAMK2D,PLD1,RAC2,MAPK1,CALM4 |
Protein Function
HCAR3 has several biochemical functions, for example, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HCAR3 itself. We selected most functions HCAR3 had, and list some proteins which have the same functions with HCAR3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | OR10C1,FZD8A,OLFR510,GPR18,VMN1R47,GPR125,TAS2R103,S1PR5B,OLFR495,PTGER1B |
Interacting Protein
HCAR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCAR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HCAR3.
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References
- Paul, KB; Thompson, JT; et al. Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors. TOXICOLOGY IN VITRO 27:2049-2060(2013).
- Chen, T; Tompkins, LM; et al. A Single Amino Acid Controls the Functional Switch of Human Constitutive Androstane Receptor (CAR) 1 to the Xenobiotic-Sensitive Splicing Variant CAR3. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 332:106-115(2010).
