GYPB
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Official Full Name
glycophorin B (MNS blood group) -
Overview
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5 UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. -
Synonyms
GYPB;glycophorin B (MNS blood group);glycophorin B (includes Ss blood group) , glycophorin B (Ss blood group) , MNS;glycophorin-B;CD235b;GPB;SS;GLPB_HUMAN;PAS-3;Sialoglycoprotein delta;SS-active sialoglycoprotein;Ss blood group;glycophorin HeP2;glycophorin MiVI;MNS;GPB.NY;HGpMiVI;GYPHe.NY
Recombinant Proteins
- Human
- Pan troglodytes
- Wheat Germ
- HEK293
- Mammalian cells
- In Vitro Cell Free System
- In vitro E. coli expression system
- E.coli expression system
- Non
- GST
- Fc
- His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GYPB-4509H | Recombinant Human GYPB Protein | Wheat Germ | Human | Non |
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| GYPB-4510H | Recombinant Human GYPB Protein, GST-tagged | Wheat Germ | Human | GST | 22-59 a.a. |
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| GYPB-313HCL | Recombinant Human GYPB lysate | HEK293 | Human | Non |
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| GYPB-3066H | Recombinant Human GYPB Protein (Met1-Ala59), C-Fc tagged | Mammalian cells | Human | Fc | Met1-Ala59 |
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| GYPB-3376HF | Recombinant Full Length Human GYPB Protein | In Vitro Cell Free System | Human | Full L. 720 amino acids |
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| GYPB-4288H | Recombinant Human GYPB Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | Human | His | Full L. 20-91aa |
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| RFL10312PF | Recombinant Full Length Pan Troglodytes Glycophorin-B(Gypb) Protein, His-Tagged | E.coli expression system | Pan troglodytes | His | Full L. Full Length of Mature Protein (20-123) |
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| RFL14875HF | Recombinant Full Length Human Glycophorin-B(Gypb) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length of Mature Protein (20-91aa) |
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Involved Pathway
GYPB involved in several pathways and played different roles in them. We selected most pathways GYPB participated on our site, such as Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with GYPB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Malaria | THBS2,HBB-B2,LRP1,TLR9,THBS3,HBB,ITGB2L,HBA2,IL1B,THBS4 |
Protein Function
GYPB has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GYPB itself. We selected most functions GYPB had, and list some proteins which have the same functions with GYPB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CDX4,RAB39B,STRA13,CREBBP,SNRPD3,KRTAP8-1,FOXH1,THAP3,AMIGO2,C4orf46 |
Interacting Protein
GYPB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GYPB here. Most of them are supplied by our site. Hope this information will be useful for your research of GYPB.
UBQLN1;UBQLN1
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References
- Peyrard, T; Lam, Y; et al. Anti-U-like as an alloantibody in S-s-U- and S-s-U+(var) black people. TRANSFUSION 52:622-628(2012).
- Hsu, K; Lin, YC; et al. A direct blood polymerase chain reaction approach for the determination of GP.Mur (Mi.III) and other Hil plus Miltenberger glycophorin variants. TRANSFUSION 53:962-971(2013).
