GTF2H2C

  • Official Full Name

    GTF2H2C general transcription factor IIH, polypeptide 2C [ Homo sapiens ]
  • Overview

    This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms; however, the full-length nature and biological validity of all of these variants have not been determined.
  • Synonyms

    general transcription factor IIH, polypeptide 2C;31394;Ensembl:ENSG00000183474;FLJ77682, MGC102806, MGC198575, DKFZp686P18101;general transcription factor IIH subunit 2-like protein;general transcription factor IIH polypeptide 2-like protein
Cat.# Product name Source (Host) Species Tag Protein Length Price
GTF2H2C-13597H Recombinant Human GTF2H2C, GST-tagged E.coli Human GST 1-395a.a.
GTF2H2C-2458H Recombinant Human GTF2H2C Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
GTF2H2C-529H Recombinant Human GTF2H2C Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK

    Involved Pathway

    GTF2H2C involved in several pathways and played different roles in them. We selected most pathways GTF2H2C participated on our site, such as Basal transcription factors,Nucleotide excision repair,Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Nucleotide Excision Repair GPS1,INO80E,POLE4,RPA2,GTF2H3-2,XPC,COPS8,RFC1,ERCC3,COPS7A
    Basal transcription factors GTF2E1,TBP,MNAT1,TAF1,GTF2F2,GTF2A1,TAF6,ERCC3,GTF2H1,TAF5L
    Viral carcinogenesis IL6ST,HIST1H4M,CASP8,PIK3CD,TRAF2,GTF2E2,HIST1H2BD,SYK,RANBP1,ATF4

    Protein Function

    GTF2H2C has several biochemical functions, for example, protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H2C itself. We selected most functions GTF2H2C had, and list some proteins which have the same functions with GTF2H2C. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding RAG2,EWSR1A,ACE,PHRF1,SHARPIN,NR6A1,BIRC7,MSL2,TRIM43A,RNF126
    protein binding CD160,CHEK1,BCL2L15,SUN1,COPS7A,AGO2,CYSLTR2,SLC3A1,LMO1,HPS6

    Interacting Protein

    GTF2H2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H2C here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H2C.

    ERCC2;GTF2H3;DZIP3;SUV39H1

    Resources

    References

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