GTF2E2
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Official Full Name
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -
Overview
The human Transcription Factor IIE (TFIIE) is composed of 56 kDa (alpha) and 34 kDa (beta) subunits and is shown to be a heterotetramer. The 56 kDa subunit contains a region similar to a zinc-binding domain and a region sharing homology with the catalytic loop of a kinase domain. TFIIE binds to RNA polymerase II in solution and joins the preinitiation complex probably concomitant with RNA polymerase II and TFIIF. alpha-TFIIE beta is an af?nity-puri?ed rabbit polyclonal antibody raised against a recombinant full-length p34 subunit of the TFIIE complex. -
Synonyms
GTF2E2;general transcription factor IIE, polypeptide 2, beta 34kDa;general transcription factor IIE, polypeptide 2 (beta subunit, 34kD);transcription initiation factor IIE subunit beta;FE;TF2E2;TFIIE B;TFIIE-beta;general transcription factor IIE subunit 2;TFIIE-B
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- Non
- His
- GST
- His&Fc&Avi
Involved Pathway
GTF2E2 involved in several pathways and played different roles in them. We selected most pathways GTF2E2 participated on our site, such as Basal transcription factors,Epstein-Barr virus infection,Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2E2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Basal transcription factors | GTF2H2C_2,GTF2F1,TAF11,TAF7,GTF2A1L,GTF2B,TAF12,TAF10,TBPL1,TAF6 |
| Epstein-Barr virus infection | PSMD4,HLA-DQB1,POLR2A,PSMD8,MAPK10,H2-Q10,POLR2K,HSPB1,MAP3K7,TRAF2 |
| Viral carcinogenesis | HIST1H2BL,HIST1H4D,UBE3A,HNRNPK,TRADD,SRF,TRAF2,MRPS18B,POLB,HIST1H4J |
Protein Function
GTF2E2 has several biochemical functions, for example, DNA binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2E2 itself. We selected most functions GTF2E2 had, and list some proteins which have the same functions with GTF2E2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | SP9,MAFBB,ASCL3,ZNF800,ZFP770,RB1,ZBTB16A,ZNF276,TAF1A,GM14479 |
| poly(A) RNA binding | CDC40,DDX54,HSD17B10,H2-Q10,ZCRB1,RBM15B,CDK5R2,IPO5,RPUSD4,MACF1 |
| protein binding | SOX1,ATXN10,DCUN1D1,USP10,CHD4,EPHB1,ZBTB25,IL23R,MIF,DNM1L |
Interacting Protein
GTF2E2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2E2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2E2.
GTF2E1;MCC;pst;ssdna_dtdg
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