GSS
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Official Full Name
glutathione synthetase -
Overview
Glutathione (GSH), a ubiquitous low molecular mass thiol, is important for a variety of biological functions including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. GSH synthetase acts a -
Synonyms
GSS;glutathione synthetase;GSH-S;GSH synthetase;glutathione synthase;GSHS;MGC14098
Recombinant Proteins
- Zebrafish
- Human
- Rat
- Cynomolgus
- Mouse
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- HEK293T
- E. coli
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
GSS involved in several pathways and played different roles in them. We selected most pathways GSS participated on our site, such as Cysteine and methionine metabolism,Glutathione metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cysteine and methionine metabolism | SMS,LDHC,MDH1,LDHAL6A,GOT1,DNMT3A,ENOPH1,DNMT3AB,AHCYL2,AGXT2 |
| Glutathione metabolism | G6PD,MGST2,GGT1,GSTM7,GPX5,MGST1.2,GPX8,SMS,MGST1.1,MGST1 |
| Metabolic pathways | LDHB,OAT,GALE,RFK,NT5C1B,NDST4,CBSB,APIP,PMVK,PHYKPL |
Protein Function
GSS has several biochemical functions, for example, ATP binding,glutathione binding,glutathione synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSS itself. We selected most functions GSS had, and list some proteins which have the same functions with GSS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glycine binding | GLRA2,SIX2A,GNMT,ALAS2,GLRA1,GLDC,GLRA4A,SRR,GRIN1,GLRA4B |
| glutathione binding | LTC4S,PTGESL,MGST1,GSTM4,LANCL1,GPX1,PTGES2,GSTM2,GSTM1,GSTP2 |
| protein binding | EIF6,PPP2R5B,UPF1,HTRA2,KCTD13,TMEM74,CNPY2,PRKG1,PRKAA2,NIPAL1 |
| magnesium ion binding | ENO2,NT5C3B,WRN,BPNT1,STK3,MTPAP,DUT,ADSS,ERN2,PKM |
| ATP binding | MINK1,PI4KA,KIF2C,ABCD3A,GK2,ATAD5,DDX6,FLJ11011L,NMRK2,CHTF18 |
| protein homodimerization activity | ABCB10,DMRTA2,MYOM1,AIMP1,LRRC41,BARD1,CDA,RPL7,OXCT1,DMRT3 |
Interacting Protein
GSS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSS here. Most of them are supplied by our site. Hope this information will be useful for your research of GSS.
TERF1;GAPDH;IRF3
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References
- Fujita, K; Shimomura, M; et al. Serum Fucosylated Haptoglobin as a Novel Prognostic Biomarker Predicting High-Gleason Prostate Cancer. PROSTATE 74:1052-1058(2014).
- Jones, M; Odunsi, S; et al. Gerstmann-Straussler-Scheinker disease Novel PRNP mutation and VGKC-complex antibodies. NEUROLOGY 82:2107-2111(2014).
