GSK3β
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Official Full Name
Glycogen Synthase Kinase 3 Beta -
Overview
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
GSK3β;glycogen synthase kinase 3 beta;Glycogen synthase kinase-3 beta;GSK-3 beta;EC 2.7.11.26;glycogen synthase kinase -3 beta;GSK3 beta isoform
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Involved Pathway
GSK3β involved in several pathways and played different roles in them. We selected most pathways GSK3β participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GSK3β were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
GSK3β has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GSK3β itself. We selected most functions GSK3β had, and list some proteins which have the same functions with GSK3β. You can find most of the proteins on our site.
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Interacting Protein
GSK3β has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSK3β here. Most of them are supplied by our site. Hope this information will be useful for your research of GSK3β.
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