GRWD1
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Official Full Name
glutamate-rich WD repeat containing 1 -
Overview
This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical;role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1;ubiquitin E3 ligase. -
Synonyms
GRWD1;glutamate-rich WD repeat containing 1;glutamate-rich WD repeat-containing protein 1;GRWD;regulator of ribosome biogenesis 1 homolog (S. cerevisiae);RRB1;WDR28;Glutamate rich WD repeat containing 1;Glutamate rich WD repeat containing protein 1;Glutamate rich WD repeat protein GRWD;GRWD 1;KIAA1942;Regulator of ribosome biogenesis 1 homolog;RRB 1;WD repeat domain 28;WDR 28;CUL4- and DDB1-associated WDR protein 4;CDW4
Recombinant Proteins
- Rat
- Zebrafish
- Human
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GRWD1-2725R | Recombinant Rat GRWD1 Protein | Mammalian Cell | Rat | His |
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| GRWD1-950Z | Recombinant Zebrafish GRWD1 | Mammalian Cell | Zebrafish | His |
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| GRWD1-5729HCL | Recombinant Human GRWD1 293 Cell Lysate | HEK293 | Human | Non |
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| GRWD1-2379R | Recombinant Rat GRWD1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GRWD1-2379R-B | Recombinant Rat GRWD1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GRWD1-5386H | Recombinant Human GRWD1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GRWD1-5615HF | Recombinant Full Length Human GRWD1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 446 amino acids |
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Involved Pathway
GRWD1 involved in several pathways and played different roles in them. We selected most pathways GRWD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GRWD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GRWD1 has several biochemical functions, for example, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRWD1 itself. We selected most functions GRWD1 had, and list some proteins which have the same functions with GRWD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | MBNL1,NGRN,FUS,DUSP14,UTP23,RAVER2,DIAP1,DQX1,MTIF2,SLBP |
Interacting Protein
GRWD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRWD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRWD1.
CUL4B;MAP3K14;midostaurin;ssrna_ug;GABARAP;MNDA;HDGF;GABARAPL2;WDR5;GRB2;CUL4A;WDR5B;RFWD2;SNRNP40;GABARAPL1
Resources
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References
- Gratenstein, K; Heggestad, AD; et al. The WD-repeat protein GRWD1: Potential roles in myeloid differentiation and ribosome biogenesis. GENOMICS 85:762-773(2005).
