GRIN3B
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Official Full Name
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -
Overview
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. -
Synonyms
GRIN3B;glutamate receptor, ionotropic, N-methyl-D-aspartate 3B;NR3B;GluN3B;glutamate receptor ionotropic, NMDA 3B;NMDAR3B;NMDA receptor subunit 3B;glutamate [NMDA] receptor subunit 3B;N-methyl-D-aspartate receptor subtype 3B;NMDA type glutamate receptor subunit NR3B
Recombinant Proteins
- Rat
- Mouse
- Human
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- GST
- Avi
- Fc
- Non
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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GRIN3B-2705R | Recombinant Rat GRIN3B Protein | Mammalian Cells | Rat | His |
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GRIN3B-7275M | Recombinant Mouse GRIN3B Protein | Mammalian Cells | Mouse | His |
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Grin3b-1592M | Recombinant Mouse Grin3b Protein, His&GST-tagged | E.coli | Mouse | GST&His | Ala102-Lys369 |
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GRIN3B-2359R | Recombinant Rat GRIN3B Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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GRIN3B-2359R-B | Recombinant Rat GRIN3B Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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GRIN3B-3933M | Recombinant Mouse GRIN3B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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GRIN3B-3933M-B | Recombinant Mouse GRIN3B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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GRIN3B-5347H | Recombinant Human GRIN3B Protein | Wheat Germ | Human | Non |
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GRIN3B-5540HF | Recombinant Full Length Human GRIN3B Protein | In Vitro Cell Free System | Human | Full L. 404 amino acids |
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Involved Pathway
GRIN3B involved in several pathways and played different roles in them. We selected most pathways GRIN3B participated on our site, such as cAMP signaling pathway,Neuroactive ligand-receptor interaction,Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIN3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Neuroactive ligand-receptor interaction | HTR1A,P2RY8,TAAR12G,GRPR,APLNRA,NTSR1,P2RY2,DRD1A,MTNR1BB,ADRB3A |
Cocaine addiction | PRKACG,MAOA,CREB5,CREB3L4,CDK5,GRM2,TH,SLC18A2,DDC,ATF4 |
cAMP signaling pathway | PIK3R2,ARAP3,HTR1E,PTGER3,GPR119,BAD,PTCH1,NFKBIA,GRIA1,DRD1A |
Nicotine addiction | GABRR2,GABRG1,GABRG3,GRIA1,SLC17A8,GABRA6,GRIA4,GABRA1,GRIA2,GABRR3 |
Alcoholism | HIST1H2BP,GNG13,TH,SLC6A3,HIST3H3,H2AFJ,HIST1H2BO,HIST1H3H,PPP1CB,SOS1 |
Glutamatergic synapse | SLC17A7,GNAS,SLC38A3,GRIN3A,MAPK1,GNB2,GNAQ,HOMER3,SHANK2,ITPR3 |
Protein Function
GRIN3B has several biochemical functions, for example, NMDA glutamate receptor activity,contributes_to calcium channel activity,cation channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIN3B itself. We selected most functions GRIN3B had, and list some proteins which have the same functions with GRIN3B. You can find most of the proteins on our site.
Function | Related Protein |
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ion channel activity | KCNA6A,TRPA1B,GRIK3,CACNA1SA,TRPC7A,CHRNA4B,TRPC2,KCNG4A,GRIA4B,FXYD6L |
receptor activity | CD4,ANTXRL,KLRB1B,NEO1,GRIA3B,AMHR2,SIGLEC7,CMKLR1,TNFRSF11B,ANTXR2A |
contributes_to calcium channel activity | GRIN1,GRIN2A |
neurotransmitter receptor activity | P2RY11 |
ionotropic glutamate receptor activity | GRIN1B,GRIA3B,KBP,GRIN2A,GRIA1A,GRID2,GRIK3,GRIA4A,GRIN1A,GRIA2B |
extracellular-glutamate-gated ion channel activity | GRIA1B,GRIN2BB,GRIN1,GRIK1,GRID2,GRIN2D,GRIK3,GRIA1A,GRIN1B,GRIA3 |
neurotransmitter binding | NIPSNAP1,SLC6A13,SLC6A11,GRIN1,GRIN2A |
NMDA glutamate receptor activity | GRIN2A,GRIN2B,GRIN2D,GRIN2BB,GRIN1A,GRIN3A,GRIN1B,GRIN2C |
glycine binding | SIX2A,ALAS2,GRIN3A,GSS,GNMT,GLRA4A,GRIN1,GLRA2,GLRA1,GLRA4B |
Interacting Protein
GRIN3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIN3B here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIN3B.
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