GRIN3A

  • Official Full Name

    glutamate receptor, ionotropic, N-methyl-D-aspartate 3A

  • Overview

    This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of;glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous;system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout;mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by;modulating NMDA receptor activity.

  • Synonyms

    GRIN3A;glutamate receptor, ionotropic, N-methyl-D-aspartate 3A;glutamate [NMDA] receptor subunit 3A;GluN3A;NMDAR3A;N-methyl-D-aspartate receptor subtype 3A;NR3A;NMDAR-L;FLJ45414

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
GRIN3A-13536H Recombinant Human GRIN3A, His-tagged E.coli Human His 976-1081a.a.
GRIN3A-2704R Recombinant Rat GRIN3A Protein Mammalian Cells Rat His
GRIN3A-805H Recombinant Human GRIN3A Mammalian Cells Human His
GRIN3A-2358R Recombinant Rat GRIN3A Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
GRIN3A-2358R-B Recombinant Rat GRIN3A Protein Pre-coupled Magnetic Beads HEK293 Rat
GRIN3A-2364H Recombinant Human GRIN3A Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
GRIN3A-3079H Recombinant Human GRIN3A Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
GRIN3A-3079H-B Recombinant Human GRIN3A Protein Pre-coupled Magnetic Beads HEK293 Human
Grin3a-3309M Recombinant Mouse Grin3a Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK

    Involved Pathway

    GRIN3A involved in several pathways and played different roles in them. We selected most pathways GRIN3A participated on our site, such as Alcoholism,Cocaine addiction,Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIN3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Nicotine addiction GABRA4,GABRQ,GRIN3B,GABRP,GABRR2,GABRR3,GRIA4,GABRB2,GRIN2B,GRIN2A
    Glutamatergic synapse PPP3R2,HOMER1,GNB4,PLCB4,PRKACB,GRM7,PLCB2,GRM3,GNG10,TRPC1
    Neuroactive ligand-receptor interaction AVPR2,GRIA3B,ADRA2DA,RXFP2,GABBR1,ADORA2AB,GLRA2,SSTR5,GABRB3,CALCR
    Alcoholism GRIN3B,CALM2,HIST2H2BE,PPP1CC,HIST1H2AK,H2AFX,GM14482,HIST1H2BA,HIST1H4H,CREB3L4
    Cocaine addiction MAOA,CREB5,GRM3,DRD1A,GRM2,SLC18A2,BDNF,GRIN2D,GPSM1,ATF6B
    cAMP signaling pathway ATP1A3,ACOX1,GNAI2,GRIA4,ATP1B4,RHOA,PLD1,CNGA3,CAMK2D,PIK3R2

    Protein Function

    GRIN3A has several biochemical functions, for example, NMDA glutamate receptor activity,contributes_to NMDA glutamate receptor activity,calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIN3A itself. We selected most functions GRIN3A had, and list some proteins which have the same functions with GRIN3A. You can find most of the proteins on our site.

    Function Related Protein
    calcium channel activity TRPC7A,ORAI1B,TRPV3,TRPV4,RYR2,SLC24A4,CACNA1SB,CCDC109A,TRPC3,CACNG2A
    glycine binding ALAS2,GNMT,GLRA4B,GSS,GRIN3B,GLDC,GRIN2B,SIX2A,GLRA2,GLRA4A
    protein binding STXBP4,HLX,MIB1,SPINK2,DYNLL2,ARL2BP,HELZ,APOH,FAM151B,RNF6
    NMDA glutamate receptor activity GRIN1A,GRIN2D,GRIN2BB,GRIN2C,GRIN2B,GRIN1B,GRIN3B,GRIN2A
    contributes_to NMDA glutamate receptor activity PTK2B,GRIN2A,GRIN1
    protein phosphatase 2A binding STRN,PPP2R4,IGBP1,EIF4EBP1,TP53,CTTNBP2NL,MAPT,MASTL,ANKLE2,SHC1
    identical protein binding TNN,MICALL1,AMOTL2,TP73,GRB7,Serpina1c,TTR,C14orf166,MTSS1,DAPK1
    extracellular-glutamate-gated ion channel activity GRIN1,GRIA4B,GRIA2,GRIK4,GRIN3B,GRID2,GRIK5,KBP,GRIA3,GRIN2B

    Interacting Protein

    GRIN3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIN3A here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIN3A.

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