GRIK5
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Official Full Name
glutamate receptor, ionotropic, kainate 5 -
Overview
glutamate receptor subunit KA2; associates with subunits of the GluR5-7 family to form heteromeric kainate-preferring glutamate receptpors -
Synonyms
GRIK5;glutamate receptor, ionotropic, kainate 5;glutamate receptor, ionotropic kainate 5;KA2;glutamate receptor KA2;glutamate receptor KA-2;iGlu5
Recombinant Proteins
- Rat
- Mouse
- Zebrafish
- Human
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc&Avi
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GRIK5-2699R | Recombinant Rat GRIK5 Protein | Mammalian Cells | Rat | His |
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| GRIK5-7268M | Recombinant Mouse GRIK5 Protein | Mammalian Cells | Mouse | His |
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| GRIK5-8075Z | Recombinant Zebrafish GRIK5 | Mammalian Cells | Zebrafish | His |
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| GRIK5-2353R | Recombinant Rat GRIK5 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GRIK5-2353R-B | Recombinant Rat GRIK5 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GRIK5-3930M | Recombinant Mouse GRIK5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GRIK5-3930M-B | Recombinant Mouse GRIK5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| GRIK5-5341H | Recombinant Human GRIK5 Protein | Wheat Germ | Human | Non |
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| GRIK5-5646HF | Recombinant Full Length Human GRIK5 Protein | In Vitro Cell Free System | Human | Full L. 168 amino acids |
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Involved Pathway
GRIK5 involved in several pathways and played different roles in them. We selected most pathways GRIK5 participated on our site, such as Neuroactive ligand-receptor interaction,Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIK5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | PRP2,PTAFR,TAAR7A,MTNR1BB,PTGER2B,GLP1R,TAAR10C,APLNRB,P2RY11,F2RL2 |
| Glutamatergic synapse | SLC1A6,GNAO1,GRM1,GNG5,SHANK3,SLC1A7,GNG11,SLC1A2,GRIK2,PLA2G4D |
Protein Function
GRIK5 has several biochemical functions, for example, PDZ domain binding,SH3 domain binding,extracellular-glutamate-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIK5 itself. We selected most functions GRIK5 had, and list some proteins which have the same functions with GRIK5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SH3 domain binding | EVL,ARHGAP6,ELMO3,DTX1,ITGB1BP2,CNTNAP1,PTPN12,ABI2,GJA1,FMN1 |
| protein binding | COMTD1,NOXA1,RPTOR,TMEM203,RGR,FXYD6,LCE3E,EFCAB11,ERO1LB,UACA |
| kainate selective glutamate receptor activity | GRIK2,GRIK3,GRIK1,GRIK4 |
| PDZ domain binding | PTEN,FZD7,LRP2,DTNA,SLC26A6,ACOX1,KIDINS220B,SSTR2,GJA1,GRASP |
| ionotropic glutamate receptor activity | GRIA4B,GRIN1A,GRIA1B,GRIN3B,GRIN2A,GRIN1B,GRIA3B,GRIA4A,GRIA4,GRIA2A |
| extracellular-glutamate-gated ion channel activity | GRIA3A,GRIN2BB,GRID1,GRIA3B,GRIA1B,GRIN2B,GRIN1,GRIA2,GRIN2A,GRIN2C |
| identical protein binding | RBM10,SMAD3,DVL2,GRIN3A,HCN4,SLIT2,EGFR,LCK,TLR3,TRIP10 |
| glutamate receptor activity | GRM3,GRM2,GRID2,GRM7,GRM1,GRM4,GRIK3,GRIA1,GRM8,GRM6 |
| ion channel activity | HTR3B,KCNS3B,KCNC2,TRPV2,P2RX8,FXYD6L,GRIN2BB,CHRNB3,TRPC7A,TRPM4A |
Interacting Protein
GRIK5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIK5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIK5.
Dlg4
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References
- Takenouchi, T; Hashida, N; et al. 1p34.3 Deletion Involving GRIK3: Further Clinical Implication of GRIK Family Glutamate Receptors in the Pathogenesis of Developmental Delay. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164:456-460(2014).
- Sanchez-Martin, FJ; Fan, YX; et al. Lead Induces Similar Gene Expression Changes in Brains of Gestationally Exposed Adult Mice and in Neurons Differentiated from Mouse Embryonic Stem Cells. PLOS ONE 8:-(2013).
