GREB1
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Official Full Name
growth regulation -
Overview
This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
GREB1;growth regulation;protein GREB1;gene regulated in breast cancer 1 protein;gene regulated by estrogen in breast cancer
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GREB1-3629H | Recombinant Human GREB1 protein, GST-tagged | E.coli | Human | GST | 1075-1212 aa | |
| GREB1-5753HCL | Recombinant Human GREB1 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
GREB1 involved in several pathways and played different roles in them. We selected most pathways GREB1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GREB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GREB1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GREB1 itself. We selected most functions GREB1 had, and list some proteins which have the same functions with GREB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
GREB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GREB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GREB1.
XRCC3;HMMR;BCAR3;HRAS;TGFB1;LSP1;CDKN2C;SMAD4;CASP8;PALB2;RB1CC1;q99ib8-pro_0000045596
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References
- Nguyen, NT; Vendrell, JA; et al. A functional interplay between ZNF217 and Estrogen Receptor alpha exists in luminal breast cancers. MOLECULAR ONCOLOGY 8:1441-1457(2014).
- Haynes, BP; Viale, G; et al. Differences in expression of proliferation-associated genes and RANKL across the menstrual cycle in estrogen receptor-positive primary breast cancer. BREAST CANCER RESEARCH AND TREATMENT 148:327-335(2014).
