GPR55
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Official Full Name
G protein-coupled receptor 55 -
Overview
Members of the G protein-coupled receptor (GPR) family, such as GPR55, play important roles in signal transduction from;the external environment to the inside of the cell (Sawzdargo et al., 1999 (PubMed 9931487)). -
Synonyms
GPR55;G protein-coupled receptor 55;G-protein coupled receptor 55;G protein coupled receptor 55;GPCR GPR55;GPR 55;Probable G protein coupled receptor 55
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GPR55-5783HCL | Recombinant Human GPR55 293 Cell Lysate | HEK293 | Human | Non |
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| GPR55-5252H | Recombinant Human GPR55 Protein | Wheat Germ | Human | Non |
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| GPR55-5600HF | Recombinant Full Length Human GPR55 Protein | In Vitro Cell Free System | Human | Full L. 675 amino acids |
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| GPR55-957H | Recombinant Human GPR55 Full Length Transmembrane protein(Nanodisc) | HEK293 | Human | Non | Full L. |
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| RFL24539MF | Recombinant Full Length Mouse G-Protein Coupled Receptor 55(Gpr55) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-328) |
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Involved Pathway
GPR55 involved in several pathways and played different roles in them. We selected most pathways GPR55 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR55 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signal Transduction | ABI1A,RNF31,SCT,HEBP1,RPE65A,GPR4,CRHR2,GNA13B,NRP2,GPR39 |
| Class A/1 (Rhodopsin-like receptors) | GPR17,HRH3,TAC3,PTGDR2,TRH,EDNRAB,OPN4.1,FFAR3,RLN3A,GPR39 |
| GPCR ligand binding | CRH,CASR,UTS2,FFAR3,PROKR2,QRFP,FPR-RS4,SSTR3,OXGR1A.3,EDNRA |
| G alpha (i) signalling events | S1PR1,CXCR7B,LPAR2A,CXCL13,DRD2,TAS2R3,NMU,TAS2R13,GPR18,RLN3A |
| GPCRs, Other | EMR2,GPR132,GPR56,SETD6,VMN1R49,GPR116,PROKR2,VMN1R52,S1PR1,LGR6 |
| GPCR downstream signaling | CALCRL,DRD3,RGS12,EDN3,DGKB,ARHGEF18A,RXFP2,GPR68,DGKQ,TAC2 |
| Signaling by GPCR | RGS7,EMR3,GPR65,RGS17,OR52B4,OXGR1A.1,NMB,OXGR1A.3,PENK,GPR31 |
Protein Function
GPR55 has several biochemical functions, for example, G-protein coupled receptor activity,cannabinoid receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR55 itself. We selected most functions GPR55 had, and list some proteins which have the same functions with GPR55. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | GPR39,ADCYAP1R1A,TAS1R2.1,GPR115,OLFR478,ADRB3B,OLFR492,PRLHR2B,CELSR1,TAS2R120 |
| cannabinoid receptor activity | CNR2,CNR1 |
Interacting Protein
GPR55 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR55 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR55.
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References
- Chiurchiu, V; Lanuti, M; et al. The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells. INTERNATIONAL IMMUNOLOGY 27:153-160(2015).
- Jenkin, KA; McAinch, AJ; et al. Elevated cannabinoid receptor 1 and G protein-coupled receptor 55 expression in proximal tubule cells and whole kidney exposed to diabetic conditions. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 42:256-262(2015).
