GPR37
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Official Full Name
G protein-coupled receptor 37 (endothelin receptor type B-like) -
Overview
Probable G-protein coupled receptor 37 is a protein that in humans is encoded by the GPR37 gene. -
Synonyms
GPR37;G protein-coupled receptor 37 (endothelin receptor type B-like);probable G-protein coupled receptor 37;EDNRBL;hET(B)R LP;PAELR;ETBR-LP-1;endothelin B receptor-like protein 1;Parkin-associated endothelin receptor-like receptor;hET(B)R-LP
Recombinant Proteins
- Rhesus macaque
- Rat
- Chicken
- Human
- Mouse
- Mus musculus
- Mammalian Cell
- HEK293
- Human Cell
- Wheat Germ
- In Vitro Cell Free System
- E.coli expression system
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
GPR37 involved in several pathways and played different roles in them. We selected most pathways GPR37 participated on our site, such as Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR37 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Parkinsons disease | SLC6A3,DRD1A,UBA1,NDUFS8,UCHL1,ATP5D,NDUFV2,MT-ND1,CASP9,COX7A2 |
Protein Function
GPR37 has several biochemical functions, for example, G-protein coupled peptide receptor activity,G-protein coupled receptor activity,Hsp70 protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR37 itself. We selected most functions GPR37 had, and list some proteins which have the same functions with GPR37. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptide binding | PLOD1,ERCC3,PCSK5,CMA1,NPFFR1L1,QRFPR,GPR22,TPP1,PPIA,TRHDE |
| G-protein coupled receptor activity | LPAR5A,GRM6,MRGPRA7,GPRC5B,GPR65,TAS2R109,FZD9,TAAR10A,OR52J3,FZD8A |
| protein binding | AGT,CASP10,DDR1,FANCG,HNRNPA2B1,TTC32,CPT1C,PDS5A,RNASEL,TMEM182 |
| ubiquitin protein ligase binding | AICDA,JAK1,UBE2C,FHIT,KDM4A,CUL4A,ABI2,PCBP2,CDKN1A,BCL2 |
| G-protein coupled peptide receptor activity | MCHR2,LTB4R,NPR3,GPR84,TSHR,GPR37L1,RXFP3.2B,LHCGR,LTB4R2,FSHR |
| Hsp70 protein binding | DNAJA1,DNAJB1,DNAJB2,RPS3,STIP1,DNAJC2,PPID,CDKN1B,L7RN6,C11orf73 |
| heat shock protein binding | TFAM,IRAK1,BAK1,NFKBIA,HSPA9,NFKB1,PDXP,HSPA1L,HSPA1A,HSPA8 |
| prosaposin receptor activity | GPR37L1 |
Interacting Protein
GPR37 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR37 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR37.
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References
- Meyer, RC; Giddens, MM; et al. The protective role of prosaposin and its receptors in the nervous system. BRAIN RESEARCH 1585:1-12(2014).
- Dutta, P; O'Connell, KE; et al. The protein interacting with C-kinase (PICK1) interacts with and attenuates parkin-associated endothelial-like (PAEL) receptor-mediated cell death. JOURNAL OF NEUROCHEMISTRY 130:360-373(2014).
