GPR133
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Official Full Name
G protein-coupled receptor 133 -
Overview
The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini;containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals;through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 (PubMed 15203201)). -
Synonyms
GPR133;G protein-coupled receptor 133;probable G-protein coupled receptor 133;DKFZp434B1272;PGR25;G-protein coupled receptor PGR25;FLJ16770;MGC138512;MGC138514
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GPR133-7140M | Recombinant Mouse GPR133 Protein | Mammalian Cells | Mouse | His |
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| GPR133-737H | Recombinant Human GPR133 Protein, His-tagged | HEK293 | Human | His | 1-570 a.a. |
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| GPR133-3849M | Recombinant Mouse GPR133 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GPR133-3849M-B | Recombinant Mouse GPR133 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GPR133 involved in several pathways and played different roles in them. We selected most pathways GPR133 participated on our site, such as Odorant GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR133 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Odorant GPCRs | GPR113,MRGPRB2,GPR126,VMN1R52,MRGPRB1,V1RA8,OLFR476,VMN1R48,VMN1R41,GPR158 |
Protein Function
GPR133 has several biochemical functions, for example, G-protein coupled receptor activity,transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR133 itself. We selected most functions GPR133 had, and list some proteins which have the same functions with GPR133. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transmembrane signaling receptor activity | OR12D2,KLRC1,EVI2A,CD4,TLR7,EMR4,ENG,FZD3A,CD300C,TLR2 |
| G-protein coupled receptor activity | PTGER1B,AGTR1A,GPR150,TAAR12H,RXFP2B,ADRA2DA,GPR34A,PTGER4A,GPR171,OR2B3 |
Interacting Protein
GPR133 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR133 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR133.
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References
- Hamann, J; Aust, G; et al. International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. PHARMACOLOGICAL REVIEWS 67:338-367(2015).
- Liebscher, I; Schon, J; et al. A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133 (vol 9, pg 2018, 2014). CELL REPORTS 10:1021-1021(2015).
