GPR120
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Official Full Name
O3FAR1 omega-3 fatty acid receptor 1 -
Overview
This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein;functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory;responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this;gene. -
Synonyms
GT01;PGR4;GPR120;GPR129;MGC119984;DKFZp686F0824;omega-3 fatty acid receptor 1;OTTHUMP00000032309;OTTHUMP00000032310;G protein-coupled receptor 120;G protein-coupled receptor 129;G-protein coupled receptor 120;G-protein coupled receptor 129;G protein-coupled receptor PGR4;G-protein coupled receptor GT01;G-protein coupled receptor PGR4;G-protein-coupled receptor GT01
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GPR120-5799HCL | Recombinant Human GPR120 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
GPR120 involved in several pathways and played different roles in them. We selected most pathways GPR120 participated on our site, such as Class A/1 (Rhodopsin-like receptors),Free fatty acid receptors,GPCR ligand binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR120 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by GPCR | OR4D2,ARHGEF17,OBSCN,VIP2,OPN4B,GHRH,RGS4,OR2AP1,CCL35.2,RGS21 |
| Incretin synthesis, secretion, and inactivation | SPCS3,O3far1,SLC38A8,CDX2,GRP,GPR119,PCSK1,DPP4 |
| Peptide hormone metabolism | PCSK2,RAB27A,MBOAT4,SLC30A6,SPCS3,CPN1,SLC30A5,CPE,GZMH,BCHE |
| GPCR ligand binding | DRD3,RGS1,EDN2,LPAR2A,PTHLHA,CCR9,TRH,NMUR1,SSTR3,CXCR6 |
| Class A/1 (Rhodopsin-like receptors) | ADRa1A,RGS1,GPR65,CHRM1,EDN1,EDN2,CGA,GPR77,TRH,NPFFR2 |
| Free fatty acid receptors | GPR31,FFAR3,GPR31B |
| Metabolism of proteins | COX17,SUMF2,SPCS3,DAD1,MUC15,MAGT1,TIMM44,ODAM,DCP2,ZDHHC2 |
| Signal Transduction | FMNL3,DZIP1,RSPO3,TAS2R7,GPR37B,ROR2,RPGRIP1L,SHARPIN,ASH2L,GRK7 |
Protein Function
GPR120 has several biochemical functions, for example, fatty acid binding,NOT peptide binding,taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR120 itself. We selected most functions GPR120 had, and list some proteins which have the same functions with GPR120. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| taste receptor activity | TAS2R143,TAS2R3,TAS1R2,TAS2R13,TAS2R134,TAS1R3,TAS2R138,TAS1R1,TAS2R140,TAS2R139 |
| fatty acid binding | FABP1,ACOX2,FABP4,FABP7B,HNF4A,NDUFAB1,APOC1,FABP2,FABP7A,LBFABP |
Interacting Protein
GPR120 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR120 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR120.
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