GORASP2
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Official Full Name
golgi reassembly stacking protein 2, 55kDa -
Overview
This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. -
Synonyms
GORASP2;golgi reassembly stacking protein 2, 55kDa;golgi reassembly stacking protein 2, 55 kDa;Golgi reassembly-stacking protein 2;GOLPH6;GRASP55;GRS2;AW552058;FLJ13139;GOLPH2;Golgi phosphoprotein 6;Golgi reassembly stacking protein 2;Golgi reassembly stacking protein of 55 kDa;Golgi reassembly-stacking protein of 55 kDa;GORS2_HUMAN;p59;RP23-428O15.1
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GORASP2-13395H | Recombinant Human GORASP2, His-tagged | E.coli | Human | His | 152-452a.a. | |
| GORASP2-10968Z | Recombinant Zebrafish GORASP2 | Mammalian Cell | Zebrafish | His |
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| GORASP2-1922R | Recombinant Rhesus monkey GORASP2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| GORASP2-1964C | Recombinant Chicken GORASP2 | Mammalian Cell | Chicken | His |
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| GORASP2-5828HCL | Recombinant Human GORASP2 293 Cell Lysate | HEK293 | Human | Non |
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| GORASP2-1742R | Recombinant Rhesus Macaque GORASP2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| GORASP2-1742R-B | Recombinant Rhesus Macaque GORASP2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| GORASP2-5121H | Recombinant Human GORASP2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GORASP2-5483HF | Recombinant Full Length Human GORASP2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 452 amino acids |
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Involved Pathway
GORASP2 involved in several pathways and played different roles in them. We selected most pathways GORASP2 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Golgi Cisternae Pericentriolar Stack Reorganization, which may be useful for your reference. Also, other proteins which involved in the same pathway with GORASP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| M Phase | RCC2,ARPP19,CDCA8,CENPP,CENPE,CTDNEP1B,NIPBLB,CCDC99,MCPH1,KIF2A |
| Cell Cycle, Mitotic | NIPBLB,NIPBLA,CKS1B,CEP57,MAPRE1B,NUP50,CENPI,ENSAB,CSNK2A2,CEP72 |
| Cell cycle | CLASP1A,CUL1,ACTR1A,TUBGCP2,HIST3H2BB,VRK1,UIMC1,CDC14A,STAG1,CEP164 |
| Mitotic Prophase | CNEP1R1,SETB,ENSAA,SETA,ARPP19,NEK7,CTDNEP1,CTDNEP1A,ENSA,SMC2 |
| Golgi Cisternae Pericentriolar Stack Reorganization | GORASP1,GOLGA2,USO1,BLZF1 |
Protein Function
GORASP2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GORASP2 itself. We selected most functions GORASP2 had, and list some proteins which have the same functions with GORASP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PMP22,MPPED2,STK25,ABCB1,ACACB,PLEKHG6,SPHK1,SYT4,CTSG,IFI6 |
Interacting Protein
GORASP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GORASP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GORASP2.
RPIA;GOLGA2;TRAF2;CBLB;ACY3
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References
- Lin, WY; Hong, J; et al. The anti-HCV gene SART1 regulates EIF4G3 and GORASP2 expression through exon splicing. HEPATOLOGY 60:1058A-1058A(2014).
- Dupont, N; Jiang, SY; et al. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1 beta. EMBO JOURNAL 30:4701-4711(2011).
