GNL3
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Official Full Name
guanine nucleotide binding protein-like 3 (nucleolar) -
Overview
May be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis. -
Synonyms
GNL3;guanine nucleotide binding protein-like 3 (nucleolar);Ns;guanine nucleotide-binding protein-like 3;nucleostemin;nucleolar GTP-binding protein 3
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GNL3-13370H | Recombinant Human GNL3, His-tagged | E.coli | Human | His | 201-549a.a. | |
| GNL3-2611R | Recombinant Rat GNL3 Protein | Mammalian Cell | Rat | His |
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| GNL3-448Z | Recombinant Zebrafish GNL3 | Mammalian Cell | Zebrafish | His |
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| GNL3-7046M | Recombinant Mouse GNL3 Protein | Mammalian Cell | Mouse | His |
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| GNL3-5846HCL | Recombinant Human GNL3 293 Cell Lysate | HEK293 | Human | Non |
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| GNL3-5847HCL | Recombinant Human GNL3 293 Cell Lysate | HEK293 | Human | Non |
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| GNL3-2266R | Recombinant Rat GNL3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GNL3-2266R-B | Recombinant Rat GNL3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GNL3-3779M | Recombinant Mouse GNL3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GNL3-3779M-B | Recombinant Mouse GNL3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| GNL3-5081H | Recombinant Human GNL3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GNL3-5397HF | Recombinant Full Length Human GNL3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 549 amino acids |
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Involved Pathway
GNL3 involved in several pathways and played different roles in them. We selected most pathways GNL3 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | WDR36,NOP58,RPP40,LSG1,TBL3,RIOK2,RPP25L,UTP14A,IMP4,RRP7A |
Protein Function
GNL3 has several biochemical functions, for example, GTP binding,GTPase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNL3 itself. We selected most functions GNL3 had, and list some proteins which have the same functions with GNL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | RAB1,TUBA4A,GNAQ,RHOC,IFT22,RAB23,SEPT3,ARL2,SEPT4A,REM1 |
| poly(A) RNA binding | DDX27,HERC5,CCT4,HNRNPH2,RPS25,ZFR,CSTF2T,WDR46,TRMT1,CORO1A |
| GTPase activity | TUBA8,RAB14,TRIM23,TUBB2,RNF112,MSTO1,TUBG2,GNG10,TUBA4A,SEPT4 |
| protein binding | GP1BB,GLS2,NFYC,AP2A1,TOP3B,NR1D2,FAM86A,Car8,RHOBTB3,PI4K2A |
Interacting Protein
GNL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNL3.
AGO2;TERT;STAT3;PPP2R5A;ESR1;ESR2;PSTPIP1;SMNDC1;CIAO1;MYC;TP53
Resources
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References
- Tsai, RYL; et al. Turning a new page on nucleostemin and self-renewal. JOURNAL OF CELL SCIENCE 127:3885-3891(2014).
- Nakajima, TE; Yoshida, H; et al. Nucleostemin and TWIST as predictive markers for recurrence after neoadjuvant chemotherapy for esophageal carcinoma. CANCER SCIENCE 103:233-238(2012).
