GNL1

  • Official Full Name

    guanine nucleotide binding protein-like 1
  • Overview

    The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C.
  • Synonyms

    GNL1;guanine nucleotide binding protein-like 1;guanine nucleotide-binding protein-like 1;HSR1;GTP binding protein HSR1;Guanine nucleotide binding protein like 1;HSR1 GTP binding protein;OTTHUMP00000029186;GTP-binding protein HSR1;HSR1 GTP-binding protein

Recombinant Proteins

  • Rhesus macaque
  • Rat
  • Zebrafish
  • Mouse
  • Human
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
  • GST

    Involved Pathway

    GNL1 involved in several pathways and played different roles in them. We selected most pathways GNL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GNL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    GNL1 has several biochemical functions, for example, GTP binding,GTPase activity,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNL1 itself. We selected most functions GNL1 had, and list some proteins which have the same functions with GNL1. You can find most of the proteins on our site.

    Function Related Protein
    GTP binding RAB2A,GBP3,AK4,GNA13B,RAB1BA,RAB8B,RAB7A,GNAT2,EIF5,GBP5
    GTPase activity RASD1,TUFM,RAB42A,TUBA1B,RRAGB,RAB3AB,GTPBP10,RAB41,RAB34,GNA14
    structural molecule activity PLP1,MAP4,RLN3B,KRT76,LCE1D,CLDN7B,KRT28,CLTC,KRT12,LCE3E

    Interacting Protein

    GNL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNL1.

    GDI1;PTP4A1;ZNF212

    Resources

    References

    • Doyle, SM; Haeger, A; et al. An early secretory pathway mediated by GNOM-LIKE 1 and GNOM is essential for basal polarity establishment in Arabidopsis thaliana. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E806-E815(2015).
    • Liu, YH; Chen, YJ; et al. Single Nucleotide Polymorphisms at the PRR3, ABCF1, and GNL1 Genes in the HLA Class I Region Are Associated with Graves' Ophthalmopathy in a Gender-Dependent Manner. OPHTHALMOLOGY 121:2033-2039(2014).

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