GNA15
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Official Full Name
guanine nucleotide binding protein (G protein), alpha 15 (Gq class) -
Overview
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class) is a protein that in humans is encoded by the GNA15 gene. -
Synonyms
G16α-Subunit;Gq alpha subunit;Gq protein;Gq/11;GNA15;GNA16;guanine nucleotide binding protein (G protein), alpha 15 (Gq class);G-protein subunit alpha-15;G-protein subunit alpha-16;g alpha-15;g alpha-16;guanine nucleotide-binding protein subunit alpha-15;guanine nucleotide-binding protein subunit alpha-16;G alpha 15;G alpha 16;GNA 15;GNA 16
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- His&Trx
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GNA15-145H | Recombinant Human GNA15 Protein, His-tagged | E.coli | Human | His |
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| GNA15-2592R | Recombinant Rat GNA15 Protein | Mammalian Cell | Rat | His |
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| GNA15-7013M | Recombinant Mouse GNA15 Protein | Mammalian Cell | Mouse | His |
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| GNA15-5871HCL | Recombinant Human GNA15 293 Cell Lysate | HEK293 | Human | Non |
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| GNA15-2247R | Recombinant Rat GNA15 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GNA15-2247R-B | Recombinant Rat GNA15 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GNA15-2974H | Recombinant Human GNA15 protein, His-Trx-tagged | E.coli | Human | His&Trx | 1-374aa |
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| GNA15-3755M | Recombinant Mouse GNA15 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GNA15-3755M-B | Recombinant Mouse GNA15 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| GNA15-5040H | Recombinant Human GNA15 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GNA15-5321HF | Recombinant Full Length Human GNA15 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 374 amino acids |
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Involved Pathway
GNA15 involved in several pathways and played different roles in them. We selected most pathways GNA15 participated on our site, such as Calcium signaling pathway,Chagas disease (American trypanosomiasis),Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNA15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chagas disease (American trypanosomiasis) | PIK3R1,PIK3CG,TRAF6,TGFBR1,TLR6,IL1B,PIK3R5,PPP2R1B,TNFRSF1A,IRAK1 |
| Calcium signaling pathway | HTR7,NOS3,GRM1,GRIN2A,CACNA1G,SLC8A3,CHRM5,TACR3L,SLC25A31,MYLK |
| Amoebiasis | ACTN4,AASS,COL4A5,SERPINB1B,NFKB1,IL-8,ITGAM,SERPINB6,ACTN1,PTK2 |
Protein Function
GNA15 has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding,G-protein coupled receptor binding,GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNA15 itself. We selected most functions GNA15 had, and list some proteins which have the same functions with GNA15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| signal transducer activity | RGRA,AGTR1B,MC5RA,TAAR12C,MAPKAPK5,GNG8,TAS2R108,VMN1R43,TAAR4,VMN1R54 |
| GTP binding | RAP1B,RAB31,RAN,IFT27,RAB5C,RHOB,SEPT2,RAB18B,RAP2C,NUDT16 |
| G-protein coupled receptor binding | QRFP,SFTPBB,GPRC5B,NPFFL,FCN1,S1PR1,GNA13B,GNA15.4,AKAP5,ADORA1 |
| G-protein beta/gamma-subunit complex binding | GNA13,GNA13B,GNA11,PIK3R5,GNA15.4,GNAO1B,CETN4,GNAV1,GNA14,GNAO1 |
| metal ion binding | Gh,GNAZ,ZNF680,DAGLB,YY1A,COL1A2,ARMC1,ZSCAN21,FYN,DMRT3A |
| GTPase activity | RAB3DA,RAP1GAP,RAB33B,RAB6B,GTPBP1L,RHOG,RAB25,GBP5,LRRK2,EEF1A1B |
Interacting Protein
GNA15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNA15 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNA15.
a8k1f4_human;MLF1;PSMD2;Usp19;Hacd3;AARSD1;q9hav2_human;CACYBP;FKBPL
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References
- Chew, KS; Schmidt, TM; et al. Loss of G(q11) Genes Does Not Abolish Melanopsin Phototransduction. PLOS ONE 9:-(2014).
- Gu, S; Su, PX; et al. Comparison of gene expression profiles and related pathways in chronic thromboembolic pulmonary hypertension. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 33:277-300(2014).
