GIMAP5
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Official Full Name
GTPase, IMAP family member 5 -
Overview
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. -
Synonyms
GIMAP5;GTPase, IMAP family member 5;IAN4L1, immune associated nucleotide 4 like 1 (mouse);GTPase IMAP family member 5;HIMAP3;IAN4;IAN4L1;IAN5;IMAP3;FLJ11296;GIMAP 5;hIAN5;IAN 5;Immune associated nucleotide 4 like 1;Immunity associated nucleotide 4 like 1 protein;Immunity associated protein 3;immunity-associated nucleotide 5 protein;inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5;IROD;IAN-5
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- His&Fc&Avi
- GST
Involved Pathway
GIMAP5 involved in several pathways and played different roles in them. We selected most pathways GIMAP5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GIMAP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GIMAP5 has several biochemical functions, for example, GTP binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GIMAP5 itself. We selected most functions GIMAP5 had, and list some proteins which have the same functions with GIMAP5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MAPK9,RCOR2,BACH1,LRRC20,HARS2,TUB,WWTR1,FASLG,ZSCAN1,CLNK |
| GTP binding | IFT22,RAB7L1,RAB3AB,SUCLG2,ATL2,RAP1B,TUBB1,CDC42L2,TUBB4B,RIT1 |
Interacting Protein
GIMAP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GIMAP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GIMAP5.
STX4;LDLRAD1;LSMEM2;EDA;GRAMD3;vpu
Resources
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References
- Webb, LMC; Pascall, JC; et al. Generation and Characterisation of Mice Deficient in the Multi-GTPase Domain Containing Protein, GIMAP8. PLOS ONE 9:-(2014).
- Wang, CH; Chen, YF; et al. Cisd2 modulates the differentiation and functioning of adipocytes by regulating intracellular Ca2+ homeostasis. HUMAN MOLECULAR GENETICS 23:4770-4785(2014).
