GGA3
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Official Full Name
golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -
Overview
GGA3 is a member of the GGA family of proteins which also includes GGA1 and GGA2. These proteins consist of four distinct segments: a VHS domain that binds the di-leucine sorting signal DXXLL; a GAT domain that binds Arf-GTP; a hinge region that recruits -
Synonyms
GGA3;golgi-associated, gamma adaptin ear containing, ARF binding protein 3;ADP-ribosylation factor-binding protein GGA3;KIAA0154;Golgi-localized, gamma ear-containing, ARF-binding protein 3;golgi associated, gamma adaptin ear containing, ARF binding
Recombinant Proteins
- Chicken
- Zebrafish
- Human
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc
- DDK
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GGA3-2781C | Recombinant Chicken GGA3 | Mammalian Cells | Chicken | His |
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| GGA3-5509Z | Recombinant Zebrafish GGA3 | Mammalian Cells | Zebrafish | His |
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| GGA3-699HCL | Recombinant Human GGA3 cell lysate | Human | Non |
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| GGA3-1156H | Recombinant Human GGA3 protein, His&Myc-tagged | E.coli | Human | His&Myc | 1-690aa |
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| GGA3-1937H | Recombinant Human GGA3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| Gga3-3199M | Recombinant Mouse Gga3 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| GGA3-4867H | Recombinant Human GGA3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GGA3-5453HF | Recombinant Full Length Human GGA3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 690 amino acids |
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Involved Pathway
GGA3 involved in several pathways and played different roles in them. We selected most pathways GGA3 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | CTSO,DNASE2B,Ctsl,CTSK,AP3M1,LAPTM5,ARSA,GALC,LAPTM4A,IDS |
Protein Function
GGA3 has several biochemical functions, for example, ADP-ribosylation factor binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GGA3 itself. We selected most functions GGA3 had, and list some proteins which have the same functions with GGA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ADP-ribosylation factor binding | GRASP,GGA2,RAB11FIP3,RAB11FIP4,ADCYAP1R1,ZFP652,SORL1,RAB11FIP4B,RAB11FIP4A |
| protein binding | NUDT21,STX19,USP8,ZDHHC13,SOX7,TFCP2,MAGEA3,UBB,CCDC53,ASB9 |
Interacting Protein
GGA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGA3.
ARF1;IGF2R;PACS1;UBB;RABEP1;UBB;CLTC;RABGEF1
Resources
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References
- Albers, S; Inthathirath, F; et al. Nuclear 82-kDa choline acetyltransferase decreases amyloidogenic APP metabolism in neurons from APP/PS1 transgenic mice. NEUROBIOLOGY OF DISEASE 69:32-42(2014).
