GFPT1
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Official Full Name
glutamine--fructose-6-phosphate transaminase 1 -
Overview
GFAT1, glutamine:fructose-6-phosphate aminotransferase 1, is the rate-limiting enzyme of the hexosamine biosynthesis pathway. This enzyme catalyzes the conversion of fructose-6-phosphate and glutamine to glucosamine-6-phosphate and glutamate. The hexosami -
Synonyms
GFPT1;glutamine--fructose-6-phosphate transaminase 1;GFPT, glutamine fructose 6 phosphate transaminase 1;glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1;GFA;GFAT;GFAT1;hexosephosphate aminotransferase 1;D-fructose-6-phosphate a
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
GFPT1 involved in several pathways and played different roles in them. We selected most pathways GFPT1 participated on our site, such as Alanine, aspartate and glutamate metabolism,Amino sugar and nucleotide sugar metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GFPT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Insulin resistance | PPARGC1A,G6PC2,CREB3L3A,PCK2,PIK3R1,INS,NFKB1,PTPN11B,CRTC2,SLC2A4 |
| Amino sugar and nucleotide sugar metabolism | GFPT2,GPI1,UXS1,TSTA3,CYB5RL,CYB5R1,PGM3,FUK,GPIA,NAGK |
| Metabolic pathways | PRIM2,NAGK,CHSY3,ACSL3,GLB1,CNDP2,SPTLC2B,PYGL,PIGW,MAN1A1 |
| Alanine, aspartate and glutamate metabolism | ADSSL,AGXTA,FOLH1,ASS1,RIMKLA,GLUD1,IL4I1,ALDH4A1,GLSA,GLS2 |
Protein Function
GFPT1 has several biochemical functions, for example, carbohydrate binding,glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GFPT1 itself. We selected most functions GFPT1 had, and list some proteins which have the same functions with GFPT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glutamine-fructose-6-phosphate transaminase (isomerizing) activity | GFPT2 |
| carbohydrate binding | PRG2,CLC,CNTN2,GRIFIN,LGALS9,GALNT11,KLRB1A,EMC7,GALNT12,SIGLEC14 |
Interacting Protein
GFPT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GFPT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GFPT1.
HLA-B;PRKAA2;MAPK8;15-deoxy-delta(12,14;bosutinib;MYC;MCM7
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