GABRD
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Official Full Name
gamma-aminobutyric acid (GABA) A receptor, subunit delta -
Overview
GABA-A receptor subunit that contributes to slow phases of GABA-induced desensitization; plays a role in synaptic transmission -
Synonyms
GABRD;gamma-aminobutyric acid (GABA) A receptor, subunit delta;gamma-aminobutyric acid receptor subunit delta;GABA(A) receptor subunit delta;gamma-aminobutyric acid (GABA-A) receptor, subunit delta;AI853201;MGC151209;MGC151213
Recombinant Proteins
- Rat
- Mouse
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GABRD-2451R | Recombinant Rat GABRD Protein | Mammalian Cells | Rat | His |
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| GABRD-6152M | Recombinant Mouse GABRD Protein | Mammalian Cells | Mouse | His |
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| GABRD-1551H | Recombinant Human GABRD Protein, His-tagged | E.coli | Human | His | Gly21-Gly193 |
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| Gabrd-1552M | Recombinant Mouse Gabrd Protein, His-tagged | E.coli | Mouse | His | Leu44-Thr223 |
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| GABRD-2107R | Recombinant Rat GABRD Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GABRD-2107R-B | Recombinant Rat GABRD Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GABRD-3432M | Recombinant Mouse GABRD Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GABRD-3432M-B | Recombinant Mouse GABRD Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GABRD involved in several pathways and played different roles in them. We selected most pathways GABRD participated on our site, such as Neuroactive ligand-receptor interaction,Retrograde endocannabinoid signaling,GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABRD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Nicotine addiction | GABRG1,GABRR1,GRIA3,GABRR2,GABRA5,GABRB3,SLC17A6,GRIN2D,GRIA4,GABRR3 |
| GABAergic synapse | GABRA5,GABRA4,GABRR2,GNG3,GABRB2,NSF,GNG2,GNAO1,SLC38A2,PRKCG |
| Retrograde endocannabinoid signaling | FAAH,PRKACB,PRKCB,GABRE,GNAI2,GABRB1,PLCB3,GNG10,MAPK10,MAPK13 |
| Neuroactive ligand-receptor interaction | TAAR14B,GRIA2,PPYR1,NMUR2,AGTR1B,P2RX6,PTGER1B,NPY2R,HRH1,PRSS3 |
Protein Function
GABRD has several biochemical functions, for example, GABA-A receptor activity,chloride channel activity,extracellular ligand-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GABRD itself. We selected most functions GABRD had, and list some proteins which have the same functions with GABRD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| extracellular ligand-gated ion channel activity | CHRNA2A,GABRR3A,CHRNB3,GABRP,GABRZ,CHRNB3A,CHRNA10A,SIX2A,GABRR3,GLRA4A |
| chloride channel activity | CLIC6,BEST1,FXYD1,CLIC1,GABRG1,GABRA5,CLCC1,GABRE,APOL1,CLCN5 |
| GABA-A receptor activity | GABRG2,GABRB3,GABRR2A,GABRZ,GABRR1,GABRA6A,GABRB1,GABRB2,GABRR3,GABRR2 |
Interacting Protein
GABRD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABRD here. Most of them are supplied by our site. Hope this information will be useful for your research of GABRD.
Resources
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References
- Takano, K; Yatabe, MS; et al. Characteristic Expressions of GABA Receptors and GABA Producing/Transporting Molecules in Rat Kidney. PLOS ONE 9:-(2014).
- Paul, J; Zeilhofer, HU; et al. Selective Distribution of GABA(A) Receptor Subtypes in Mouse Spinal Dorsal Horn Neurons and Primary Afferents. JOURNAL OF COMPARATIVE NEUROLOGY 520:3895-3911(2012).
